APELLIS PHARMACEUTICALS INC

Ticker: APLS CUSIP: 03753U106 Class: Common Stock

Brevan Howard Capital Management LP's Holding History (CIK: 0001512857)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 16,117 Value ($000) $405 Avg Close $23.46 Range $18.75 - $30.48

Q3 2025

Shares 91,021 Value ($000) $2,060 Avg Close $23.32 Range $17.35 - $28.97

Q3 2024

Shares 19,928 Value ($000) $575 Avg Close $37.03 Range $28.32 - $42.47

Q1 2024

Shares 10,415 Value ($000) $612 Avg Close $63.75 Range $53.19 - $73.80

Q4 2023

Shares 4,343 Value ($000) $260 Avg Close $50.73 Range $36.31 - $66.30

Q2 2023

Shares 2,276 Value ($000) $207 Avg Close $86.28 Range $73.80 - $94.75

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	16,117	$405	$23.46	$18.75 - $30.48
Q3 2025	91,021	$2,060	$23.32	$17.35 - $28.97
Q3 2024	19,928	$575	$37.03	$28.32 - $42.47
Q1 2024	10,415	$612	$63.75	$53.19 - $73.80
Q4 2023	4,343	$260	$50.73	$36.31 - $66.30
Q2 2023	2,276	$207	$86.28	$73.80 - $94.75