APELLIS PHARMACEUTICALS INC

Ticker: APLS CUSIP: 03753U106 Class: Common Stock

JANE STREET GROUP, LLC's Holding History (CIK: 0001595888)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 50,114 Value ($000) $1,259 Avg Close $23.46 Range $18.75 - $30.48

Q3 2025

Shares 293,199 Value ($000) $6,635 Avg Close $23.32 Range $17.35 - $28.97

Q2 2025

Shares 246,199 Value ($000) $4,262 Avg Close $18.51 Range $16.10 - $23.77

Q1 2025

Shares 256,092 Value ($000) $5,601 Avg Close $27.62 Range $21.70 - $35.57

Q4 2024

Shares 95,985 Value ($000) $3,063 Avg Close $30.07 Range $24.34 - $35.72

Q3 2024

Shares 19,280 Value ($000) $556 Avg Close $37.03 Range $28.32 - $42.47

Q2 2024

Shares 200,889 Value ($000) $7,706 Avg Close $45.29 Range $37.00 - $59.91

Q1 2024

Shares 129,009 Value ($000) $7,583 Avg Close $63.75 Range $53.19 - $73.80

Q4 2023

Shares 434,701 Value ($000) $26,021 Avg Close $50.73 Range $36.31 - $66.30

Q3 2023

Shares 273,226 Value ($000) $10,394 Avg Close $43.93 Range $19.83 - $91.35

Q2 2023

Shares 481,082 Value ($000) $43,827 Avg Close $86.28 Range $73.80 - $94.75

Q1 2023

Shares 63,384 Value ($000) $4,181 Avg Close $57.70 Range $44.92 - $70.75

Q4 2022

Shares 14,021 Value ($000) $725 Avg Close $53.04 Range $42.15 - $66.80

Q3 2022

Shares 16,998 Value ($000) $1,161 Avg Close $59.17 Range $44.07 - $70.00

Q2 2022

Shares 94,582 Value ($000) $4,277 Avg Close $45.59 Range $33.32 - $60.20

Q1 2022

Shares 75,110 Value ($000) $3,817 Avg Close $44.15 Range $33.50 - $54.51

Q4 2021

Shares 100,711 Value ($000) $4,761 Avg Close $39.37 Range $30.17 - $50.31

Q3 2021

Shares 15,943 Value ($000) $525 Avg Close $56.19 Range $27.50 - $73.00

Q2 2021

Shares 34,562 Value ($000) $2,184 Avg Close $51.60 Range $40.53 - $66.07

Q1 2021

Shares 23,098 Value ($000) $991 Avg Close $47.32 Range $39.95 - $58.47

Q4 2020

Shares 56,952 Value ($000) $3,258 Avg Close $42.30 Range $29.80 - $58.03

Q3 2020

Shares 42,570 Value ($000) $1,284 Avg Close $29.88 Range $25.49 - $34.08

Q2 2020

Shares 22,979 Value ($000) $750 Avg Close $32.11 Range $24.34 - $39.98

Q4 2019

Shares 8,135 Value ($000) $249 Avg Close $27.68 Range $21.79 - $31.47

Q3 2019

Shares 95,724 Value ($000) $2,306 Avg Close $27.52 Range $23.83 - $33.18

Q2 2019

Shares 13,439 Value ($000) $341 Avg Close $20.35 Range $17.36 - $25.41

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	50,114	$1,259	$23.46	$18.75 - $30.48
Q3 2025	293,199	$6,635	$23.32	$17.35 - $28.97
Q2 2025	246,199	$4,262	$18.51	$16.10 - $23.77
Q1 2025	256,092	$5,601	$27.62	$21.70 - $35.57
Q4 2024	95,985	$3,063	$30.07	$24.34 - $35.72
Q3 2024	19,280	$556	$37.03	$28.32 - $42.47
Q2 2024	200,889	$7,706	$45.29	$37.00 - $59.91
Q1 2024	129,009	$7,583	$63.75	$53.19 - $73.80
Q4 2023	434,701	$26,021	$50.73	$36.31 - $66.30
Q3 2023	273,226	$10,394	$43.93	$19.83 - $91.35
Q2 2023	481,082	$43,827	$86.28	$73.80 - $94.75
Q1 2023	63,384	$4,181	$57.70	$44.92 - $70.75
Q4 2022	14,021	$725	$53.04	$42.15 - $66.80
Q3 2022	16,998	$1,161	$59.17	$44.07 - $70.00
Q2 2022	94,582	$4,277	$45.59	$33.32 - $60.20
Q1 2022	75,110	$3,817	$44.15	$33.50 - $54.51
Q4 2021	100,711	$4,761	$39.37	$30.17 - $50.31
Q3 2021	15,943	$525	$56.19	$27.50 - $73.00
Q2 2021	34,562	$2,184	$51.60	$40.53 - $66.07
Q1 2021	23,098	$991	$47.32	$39.95 - $58.47
Q4 2020	56,952	$3,258	$42.30	$29.80 - $58.03
Q3 2020	42,570	$1,284	$29.88	$25.49 - $34.08
Q2 2020	22,979	$750	$32.11	$24.34 - $39.98
Q4 2019	8,135	$249	$27.68	$21.79 - $31.47
Q3 2019	95,724	$2,306	$27.52	$23.83 - $33.18
Q2 2019	13,439	$341	$20.35	$17.36 - $25.41