APELLIS PHARMACEUTICALS INC

Ticker: APLS CUSIP: 03753U106 Class: Common Stock

Avoro Capital Advisors LLC's Holding History (CIK: 0001633313)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 12,222,222 Value ($000) $307,022 Avg Close $23.46 Range $18.75 - $30.48

Q3 2025

Shares 12,222,222 Value ($000) $276,589 Avg Close $23.32 Range $17.35 - $28.97

Q2 2025

Shares 12,222,222 Value ($000) $211,567 Avg Close $18.51 Range $16.10 - $23.77

Q1 2025

Shares 12,222,222 Value ($000) $267,300 Avg Close $27.62 Range $21.70 - $35.57

Q4 2024

Shares 12,222,222 Value ($000) $390,011 Avg Close $30.07 Range $24.34 - $35.72

Q3 2024

Shares 11,111,111 Value ($000) $320,444 Avg Close $37.03 Range $28.32 - $42.47

Q2 2024

Shares 11,111,111 Value ($000) $426,222 Avg Close $45.29 Range $37.00 - $59.91

Q1 2024

Shares 11,111,111 Value ($000) $653,111 Avg Close $63.75 Range $53.19 - $73.80

Q4 2023

Shares 11,111,111 Value ($000) $665,111 Avg Close $50.73 Range $36.31 - $66.30

Q3 2023

Shares 11,111,111 Value ($000) $422,667 Avg Close $43.93 Range $19.83 - $91.35

Q2 2023

Shares 11,111,111 Value ($000) $1,012,222 Avg Close $86.28 Range $73.80 - $94.75

Q1 2023

Shares 11,111,111 Value ($000) $732,889 Avg Close $57.70 Range $44.92 - $70.75

Q4 2022

Shares 10,625,000 Value ($000) $549,419 Avg Close $53.04 Range $42.15 - $66.80

Q3 2022

Shares 10,125,000 Value ($000) $691,538 Avg Close $59.17 Range $44.07 - $70.00

Q2 2022

Shares 9,805,000 Value ($000) $443,382 Avg Close $45.59 Range $33.32 - $60.20

Q1 2022

Shares 9,450,000 Value ($000) $480,155 Avg Close $44.15 Range $33.50 - $54.51

Q4 2021

Shares 8,555,555 Value ($000) $404,507 Avg Close $39.37 Range $30.17 - $50.31

Q3 2021

Shares 5,000,000 Value ($000) $164,800 Avg Close $56.19 Range $27.50 - $73.00

Q2 2021

Shares 1,005,230 Value ($000) $63,531 Avg Close $51.60 Range $40.53 - $66.07

Q1 2021

Shares 1,000,000 Value ($000) $42,910 Avg Close $47.32 Range $39.95 - $58.47

Q1 2018

Shares 396,635 Value ($000) $7,454 Avg Close $19.65 Range $13.54 - $27.53

Q4 2017

Shares 396,635 Value ($000) $7,316 Avg Close $14.72 Range $12.45 - $24.17

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	12,222,222	$307,022	$23.46	$18.75 - $30.48
Q3 2025	12,222,222	$276,589	$23.32	$17.35 - $28.97
Q2 2025	12,222,222	$211,567	$18.51	$16.10 - $23.77
Q1 2025	12,222,222	$267,300	$27.62	$21.70 - $35.57
Q4 2024	12,222,222	$390,011	$30.07	$24.34 - $35.72
Q3 2024	11,111,111	$320,444	$37.03	$28.32 - $42.47
Q2 2024	11,111,111	$426,222	$45.29	$37.00 - $59.91
Q1 2024	11,111,111	$653,111	$63.75	$53.19 - $73.80
Q4 2023	11,111,111	$665,111	$50.73	$36.31 - $66.30
Q3 2023	11,111,111	$422,667	$43.93	$19.83 - $91.35
Q2 2023	11,111,111	$1,012,222	$86.28	$73.80 - $94.75
Q1 2023	11,111,111	$732,889	$57.70	$44.92 - $70.75
Q4 2022	10,625,000	$549,419	$53.04	$42.15 - $66.80
Q3 2022	10,125,000	$691,538	$59.17	$44.07 - $70.00
Q2 2022	9,805,000	$443,382	$45.59	$33.32 - $60.20
Q1 2022	9,450,000	$480,155	$44.15	$33.50 - $54.51
Q4 2021	8,555,555	$404,507	$39.37	$30.17 - $50.31
Q3 2021	5,000,000	$164,800	$56.19	$27.50 - $73.00
Q2 2021	1,005,230	$63,531	$51.60	$40.53 - $66.07
Q1 2021	1,000,000	$42,910	$47.32	$39.95 - $58.47
Q1 2018	396,635	$7,454	$19.65	$13.54 - $27.53
Q4 2017	396,635	$7,316	$14.72	$12.45 - $24.17