APOGEE THERAPEUTICS INC

Ticker: APGE CUSIP: 03770N101 Class: Common Stock

D. E. Shaw & Co., Inc.'s Holding History (CIK: 0001009207)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 63,250 Value ($000) $4,774 Avg Close $62.99 Range $38.88 - $80.99

Q3 2025

Shares 100,570 Value ($000) $3,996 Avg Close $38.18 Range $34.34 - $47.71

Q2 2025

Shares 194,528 Value ($000) $8,448 Avg Close $38.04 Range $26.20 - $44.65

Q1 2025

Shares 8,776 Value ($000) $328 Avg Close $38.66 Range $29.10 - $50.56

Q4 2024

Shares 9,813 Value ($000) $445 Avg Close $51.00 Range $41.85 - $63.50

Q3 2024

Shares 49,662 Value ($000) $2,917 Avg Close $47.91 Range $36.60 - $60.82

Q2 2024

Shares 52,026 Value ($000) $2,047 Avg Close $48.54 Range $36.26 - $68.21

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	63,250	$4,774	$62.99	$38.88 - $80.99
Q3 2025	100,570	$3,996	$38.18	$34.34 - $47.71
Q2 2025	194,528	$8,448	$38.04	$26.20 - $44.65
Q1 2025	8,776	$328	$38.66	$29.10 - $50.56
Q4 2024	9,813	$445	$51.00	$41.85 - $63.50
Q3 2024	49,662	$2,917	$47.91	$36.60 - $60.82
Q2 2024	52,026	$2,047	$48.54	$36.26 - $68.21