APOGEE THERAPEUTICS INC

Ticker: APGE CUSIP: 03770N101 Class: Common Stock

RA CAPITAL MANAGEMENT, L.P.'s Holding History (CIK: 0001346824)

Note: Option positions (PUT/CALL) are excluded.

Q1 2025

Shares 1,569,491 Value ($000) $58,636 Avg Close $38.66 Range $29.10 - $50.56

Q4 2024

Shares 1,569,491 Value ($000) $71,098 Avg Close $51.00 Range $41.85 - $63.50

Q3 2024

Shares 1,961,863 Value ($000) $115,240 Avg Close $47.91 Range $36.60 - $60.82

Q2 2024

Shares 1,961,863 Value ($000) $77,199 Avg Close $48.54 Range $36.26 - $68.21

Q1 2024

Shares 1,977,901 Value ($000) $131,432 Avg Close $43.66 Range $27.05 - $72.29

Q4 2023

Shares 1,977,901 Value ($000) $55,263 Avg Close $20.05 Range $14.19 - $33.08

Q3 2023

Shares 1,977,901 Value ($000) $42,129 Avg Close $22.03 Range $18.99 - $25.54

Period	Shares	Value ($000)	Average Close	Price Range
Q1 2025	1,569,491	$58,636	$38.66	$29.10 - $50.56
Q4 2024	1,569,491	$71,098	$51.00	$41.85 - $63.50
Q3 2024	1,961,863	$115,240	$47.91	$36.60 - $60.82
Q2 2024	1,961,863	$77,199	$48.54	$36.26 - $68.21
Q1 2024	1,977,901	$131,432	$43.66	$27.05 - $72.29
Q4 2023	1,977,901	$55,263	$20.05	$14.19 - $33.08
Q3 2023	1,977,901	$42,129	$22.03	$18.99 - $25.54