APOGEE THERAPEUTICS INC

Ticker: APGE CUSIP: 03770N101 Class: Common Stock

TWO SIGMA ADVISERS, LP's Holding History (CIK: 0001478735)

Note: Option positions (PUT/CALL) are excluded.

Q2 2025

Shares 6,300 Value ($000) $274 Avg Close $38.04 Range $26.20 - $44.65

Q1 2025

Shares 67,700 Value ($000) $2,529 Avg Close $38.66 Range $29.10 - $50.56

Q4 2024

Shares 71,500 Value ($000) $3,239 Avg Close $51.00 Range $41.85 - $63.50

Q3 2024

Shares 47,200 Value ($000) $2,773 Avg Close $47.91 Range $36.60 - $60.82

Q2 2024

Shares 52,400 Value ($000) $2,062 Avg Close $48.54 Range $36.26 - $68.21

Q1 2024

Shares 4,100 Value ($000) $272 Avg Close $43.66 Range $27.05 - $72.29

Period	Shares	Value ($000)	Average Close	Price Range
Q2 2025	6,300	$274	$38.04	$26.20 - $44.65
Q1 2025	67,700	$2,529	$38.66	$29.10 - $50.56
Q4 2024	71,500	$3,239	$51.00	$41.85 - $63.50
Q3 2024	47,200	$2,773	$47.91	$36.60 - $60.82
Q2 2024	52,400	$2,062	$48.54	$36.26 - $68.21
Q1 2024	4,100	$272	$43.66	$27.05 - $72.29