APOGEE THERAPEUTICS INC

Ticker: APGE CUSIP: 03770N101 Class: Common Stock

Sofinnova Investments, Inc.'s Holding History (CIK: 0001631134)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 534,845 Value ($000) $40,370 Avg Close $62.99 Range $38.88 - $80.99

Q3 2025

Shares 565,417 Value ($000) $22,464 Avg Close $38.18 Range $34.34 - $47.71

Q2 2025

Shares 76,180 Value ($000) $3,308 Avg Close $38.04 Range $26.20 - $44.65

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	534,845	$40,370	$62.99	$38.88 - $80.99
Q3 2025	565,417	$22,464	$38.18	$34.34 - $47.71
Q2 2025	76,180	$3,308	$38.04	$26.20 - $44.65