APOGEE THERAPEUTICS INC

Ticker: APGE CUSIP: 03770N101 Class: Common Stock

Polar Capital Holdings Plc's Holding History (CIK: 0001837309)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 503,539 Value ($000) $38,007 Avg Close $62.99 Range $38.88 - $80.99

Q3 2025

Shares 524,094 Value ($000) $20,822 Avg Close $38.18 Range $34.34 - $47.71

Q2 2025

Shares 495,000 Value ($000) $21,498 Avg Close $38.04 Range $26.20 - $44.65

Q1 2025

Shares 550,000 Value ($000) $20,548 Avg Close $38.66 Range $29.10 - $50.56

Q2 2024

Shares 250,000 Value ($000) $9,838 Avg Close $48.54 Range $36.26 - $68.21

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	503,539	$38,007	$62.99	$38.88 - $80.99
Q3 2025	524,094	$20,822	$38.18	$34.34 - $47.71
Q2 2025	495,000	$21,498	$38.04	$26.20 - $44.65
Q1 2025	550,000	$20,548	$38.66	$29.10 - $50.56
Q2 2024	250,000	$9,838	$48.54	$36.26 - $68.21