APTOSE BIOSCIENCES INC

CUSIP: 03835T200 Class: Stock

Opaleye Management Inc.'s Holding History (CIK: 0001595855)

Note: Option positions (PUT/CALL) are excluded.

Q3 2021
Shares 549,000 Value ($000) $1,197 Avg Close — Range —
Q2 2021
Shares 980,000 Value ($000) $3,254 Avg Close — Range —
Q1 2021
Shares 871,800 Value ($000) $5,209 Avg Close — Range —
Q4 2020
Shares 800,000 Value ($000) $3,504 Avg Close — Range —
Q3 2020
Shares 1,799,000 Value ($000) $10,794 Avg Close — Range —
Q2 2020
Shares 3,130,000 Value ($000) $19,750 Avg Close — Range —
Q1 2020
Shares 4,022,000 Value ($000) $23,891 Avg Close — Range —
Q4 2019
Shares 4,085,000 Value ($000) $23,162 Avg Close — Range —
Q3 2019
Shares 720,000 Value ($000) $1,501 Avg Close — Range —