ARDELYX INC

Ticker: ARDX CUSIP: 039697107 Class: Common Stock

TWO SIGMA ADVISERS, LP's Holding History (CIK: 0001478735)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 1,348,700 Value ($000) $7,863 Avg Close $5.57 Range $4.71 - $6.73

Q3 2025

Shares 1,614,600 Value ($000) $8,896 Avg Close $5.43 Range $3.80 - $6.78

Q2 2025

Shares 1,236,500 Value ($000) $4,847 Avg Close $4.13 Range $3.21 - $5.64

Q1 2025

Shares 594,100 Value ($000) $2,917 Avg Close $5.37 Range $4.67 - $6.55

Q4 2024

Shares 593,700 Value ($000) $3,010 Avg Close $5.52 Range $4.32 - $7.04

Q3 2024

Shares 193,600 Value ($000) $1,334 Avg Close $5.90 Range $5.07 - $8.06

Q2 2024

Shares 443,729 Value ($000) $3,288 Avg Close $7.03 Range $5.76 - $9.33

Q1 2024

Shares 433,600 Value ($000) $3,165 Avg Close $8.55 Range $5.92 - $10.13

Q2 2023

Shares 394,300 Value ($000) $1,337 Avg Close $4.10 Range $3.19 - $5.13

Q1 2023

Shares 1,628,800 Value ($000) $7,802 Avg Close $3.37 Range $2.63 - $4.94

Q2 2022

Shares 48,900 Value ($000) $29 Avg Close $0.74 Range $0.49 - $1.38

Q1 2022

Shares 98,900 Value ($000) $106 Avg Close $0.89 Range $0.58 - $1.20

Q4 2021

Shares 64,000 Value ($000) $70 Avg Close $1.19 Range $0.82 - $1.92

Q2 2021

Shares 269,000 Value ($000) $2,039 Avg Close $7.39 Range $6.22 - $9.23

Q1 2021

Shares 722,000 Value ($000) $4,780 Avg Close $6.86 Range $5.91 - $7.86

Q4 2020

Shares 522,000 Value ($000) $3,377 Avg Close $5.93 Range $4.96 - $7.35

Q3 2020

Shares 544,000 Value ($000) $2,856 Avg Close $6.01 Range $5.21 - $7.19

Q2 2020

Shares 455,900 Value ($000) $3,155 Avg Close $6.95 Range $5.24 - $8.33

Q1 2020

Shares 258,600 Value ($000) $1,470 Avg Close $6.80 Range $4.22 - $8.81

Q4 2019

Shares 145,800 Value ($000) $1,094 Avg Close $6.08 Range $4.16 - $8.49

Q3 2019

Shares 142,000 Value ($000) $667 Avg Close $3.47 Range $2.10 - $6.78

Q2 2019

Shares 145,500 Value ($000) $391 Avg Close $3.01 Range $2.35 - $3.90

Q1 2019

Shares 185,900 Value ($000) $521 Avg Close $2.60 Range $1.70 - $3.45

Q4 2018

Shares 244,700 Value ($000) $438 Avg Close $2.94 Range $1.60 - $4.42

Q3 2018

Shares 333,400 Value ($000) $1,450 Avg Close $4.16 Range $3.58 - $4.70

Q2 2018

Shares 341,800 Value ($000) $1,265 Avg Close $4.64 Range $3.60 - $5.90

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	1,348,700	$7,863	$5.57	$4.71 - $6.73
Q3 2025	1,614,600	$8,896	$5.43	$3.80 - $6.78
Q2 2025	1,236,500	$4,847	$4.13	$3.21 - $5.64
Q1 2025	594,100	$2,917	$5.37	$4.67 - $6.55
Q4 2024	593,700	$3,010	$5.52	$4.32 - $7.04
Q3 2024	193,600	$1,334	$5.90	$5.07 - $8.06
Q2 2024	443,729	$3,288	$7.03	$5.76 - $9.33
Q1 2024	433,600	$3,165	$8.55	$5.92 - $10.13
Q2 2023	394,300	$1,337	$4.10	$3.19 - $5.13
Q1 2023	1,628,800	$7,802	$3.37	$2.63 - $4.94
Q2 2022	48,900	$29	$0.74	$0.49 - $1.38
Q1 2022	98,900	$106	$0.89	$0.58 - $1.20
Q4 2021	64,000	$70	$1.19	$0.82 - $1.92
Q2 2021	269,000	$2,039	$7.39	$6.22 - $9.23
Q1 2021	722,000	$4,780	$6.86	$5.91 - $7.86
Q4 2020	522,000	$3,377	$5.93	$4.96 - $7.35
Q3 2020	544,000	$2,856	$6.01	$5.21 - $7.19
Q2 2020	455,900	$3,155	$6.95	$5.24 - $8.33
Q1 2020	258,600	$1,470	$6.80	$4.22 - $8.81
Q4 2019	145,800	$1,094	$6.08	$4.16 - $8.49
Q3 2019	142,000	$667	$3.47	$2.10 - $6.78
Q2 2019	145,500	$391	$3.01	$2.35 - $3.90
Q1 2019	185,900	$521	$2.60	$1.70 - $3.45
Q4 2018	244,700	$438	$2.94	$1.60 - $4.42
Q3 2018	333,400	$1,450	$4.16	$3.58 - $4.70
Q2 2018	341,800	$1,265	$4.64	$3.60 - $5.90