ARQULE INC

CUSIP: 04269E107 Class: Common Stock

Opaleye Management Inc.'s Holding History (CIK: 0001595855)

Note: Option positions (PUT/CALL) are excluded.

Q2 2019
Shares 100,000 Value ($000) $1,101 Avg Close — Range —
Q4 2018
Shares 200,000 Value ($000) $358 Avg Close — Range —
Q3 2018
Shares 550,000 Value ($000) $3,113 Avg Close — Range —
Q2 2018
Shares 420,000 Value ($000) $2,322 Avg Close — Range —
Q3 2017
Shares 1,220,000 Value ($000) $1,354 Avg Close — Range —
Q2 2017
Shares 970,000 Value ($000) $1,203 Avg Close — Range —
Q1 2017
Shares 560,000 Value ($000) $593 Avg Close — Range —