ARROWHEAD PHARMACEUTICALS IN

Ticker: ARWR CUSIP: 04280A100 Class: Common Stock

BAKER BROS. ADVISORS LP's Holding History (CIK: 0001263508)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 2,175,645 Value ($000) $144,441 Avg Close $49.01 Range $34.38 - $72.36

Q3 2025

Shares 1,670,762 Value ($000) $57,625 Avg Close $21.98 Range $14.30 - $34.61

Q2 2025

Shares 939,174 Value ($000) $14,839 Avg Close $14.35 Range $9.57 - $17.49

Q3 2018

Shares 307,496 Value ($000) $5,895 Avg Close $16.41 Range $12.25 - $22.39

Q3 2016

Shares 1,856,967 Value ($000) $13,649 Avg Close $6.48 Range $5.29 - $8.22

Q2 2016

Shares 1,009,509 Value ($000) $5,371 Avg Close $5.71 Range $4.68 - $6.55

Q1 2016

Shares 1,009,509 Value ($000) $4,866 Avg Close $4.22 Range $3.07 - $6.05

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	2,175,645	$144,441	$49.01	$34.38 - $72.36
Q3 2025	1,670,762	$57,625	$21.98	$14.30 - $34.61
Q2 2025	939,174	$14,839	$14.35	$9.57 - $17.49
Q3 2018	307,496	$5,895	$16.41	$12.25 - $22.39
Q3 2016	1,856,967	$13,649	$6.48	$5.29 - $8.22
Q2 2016	1,009,509	$5,371	$5.71	$4.68 - $6.55
Q1 2016	1,009,509	$4,866	$4.22	$3.07 - $6.05