ARROWHEAD PHARMACEUTICALS IN

Ticker: ARWR CUSIP: 04280A100 Class: Common Stock

MILLENNIUM MANAGEMENT LLC's Holding History (CIK: 0001273087)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 45,018 Value ($000) $2,989 Avg Close $49.01 Range $34.38 - $72.36

Q3 2025

Shares 109,807 Value ($000) $3,787 Avg Close $21.98 Range $14.30 - $34.61

Q2 2025

Shares 169,041 Value ($000) $2,671 Avg Close $14.35 Range $9.57 - $17.49

Q1 2025

Shares 690,796 Value ($000) $8,801 Avg Close $18.18 Range $12.14 - $21.84

Q4 2024

Shares 914,550 Value ($000) $17,194 Avg Close $20.59 Range $17.05 - $27.34

Q3 2024

Shares 645,604 Value ($000) $12,505 Avg Close $24.41 Range $19.07 - $30.41

Q2 2024

Shares 529,251 Value ($000) $13,755 Avg Close $24.57 Range $21.39 - $28.50

Q1 2024

Shares 326,971 Value ($000) $9,351 Avg Close $31.99 Range $27.00 - $39.83

Q3 2023

Shares 308,613 Value ($000) $8,292 Avg Close $30.63 Range $26.04 - $36.43

Q2 2023

Shares 328,393 Value ($000) $11,710 Avg Close $34.48 Range $24.64 - $42.48

Q1 2023

Shares 969,394 Value ($000) $25 Avg Close $31.45 Range $23.09 - $41.03

Q4 2022

Shares 575,624 Value ($000) $23 Avg Close $33.13 Range $27.75 - $40.62

Q3 2022

Shares 78,714 Value ($000) $2,601 Avg Close $40.36 Range $29.60 - $48.48

Q2 2022

Shares 137,178 Value ($000) $4,830 Avg Close $37.62 Range $26.81 - $51.11

Q1 2022

Shares 139,480 Value ($000) $6,415 Avg Close $49.51 Range $38.89 - $70.09

Q4 2021

Shares 30,656 Value ($000) $2,032 Avg Close $68.71 Range $57.94 - $84.83

Q3 2021

Shares 48,019 Value ($000) $2,998 Avg Close $64.75 Range $57.92 - $86.01

Q2 2021

Shares 24,031 Value ($000) $1,990 Avg Close $74.45 Range $60.52 - $93.66

Q1 2021

Shares 30,119 Value ($000) $1,997 Avg Close $77.59 Range $60.64 - $92.60

Q4 2020

Shares 32,029 Value ($000) $2,458 Avg Close $63.95 Range $42.44 - $86.75

Q3 2020

Shares 188,244 Value ($000) $8,106 Avg Close $43.15 Range $32.86 - $53.12

Q4 2019

Shares 75,857 Value ($000) $4,812 Avg Close $49.62 Range $27.11 - $73.72

Q3 2019

Shares 7,856 Value ($000) $221 Avg Close $29.59 Range $25.68 - $36.80

Q2 2019

Shares 413,289 Value ($000) $10,952 Avg Close $21.95 Range $17.30 - $28.84

Q1 2019

Shares 943,835 Value ($000) $17,319 Avg Close $16.50 Range $11.67 - $20.60

Q4 2018

Shares 106,941 Value ($000) $1,328 Avg Close $13.67 Range $10.41 - $20.31

Q3 2018

Shares 272,061 Value ($000) $5,215 Avg Close $16.41 Range $12.25 - $22.39

Q1 2018

Shares 817,317 Value ($000) $5,893 Avg Close $6.16 Range $3.57 - $8.09

Q4 2017

Shares 1,016,427 Value ($000) $3,740 Avg Close $3.71 Range $3.01 - $4.54

Q3 2017

Shares 1,272,138 Value ($000) $5,508 Avg Close $2.38 Range $1.48 - $4.42

Q2 2017

Shares 1,477,039 Value ($000) $2,393 Avg Close $1.62 Range $1.42 - $2.04

Q1 2017

Shares 484,330 Value ($000) $896 Avg Close $1.98 Range $1.42 - $2.45

Q4 2016

Shares 1,177,293 Value ($000) $1,825 Avg Close $4.26 Range $1.20 - $7.74

Q3 2016

Shares 33,620 Value ($000) $247 Avg Close $6.48 Range $5.29 - $8.22

Q2 2016

Shares 29,511 Value ($000) $157 Avg Close $5.71 Range $4.68 - $6.55

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	45,018	$2,989	$49.01	$34.38 - $72.36
Q3 2025	109,807	$3,787	$21.98	$14.30 - $34.61
Q2 2025	169,041	$2,671	$14.35	$9.57 - $17.49
Q1 2025	690,796	$8,801	$18.18	$12.14 - $21.84
Q4 2024	914,550	$17,194	$20.59	$17.05 - $27.34
Q3 2024	645,604	$12,505	$24.41	$19.07 - $30.41
Q2 2024	529,251	$13,755	$24.57	$21.39 - $28.50
Q1 2024	326,971	$9,351	$31.99	$27.00 - $39.83
Q3 2023	308,613	$8,292	$30.63	$26.04 - $36.43
Q2 2023	328,393	$11,710	$34.48	$24.64 - $42.48
Q1 2023	969,394	$25	$31.45	$23.09 - $41.03
Q4 2022	575,624	$23	$33.13	$27.75 - $40.62
Q3 2022	78,714	$2,601	$40.36	$29.60 - $48.48
Q2 2022	137,178	$4,830	$37.62	$26.81 - $51.11
Q1 2022	139,480	$6,415	$49.51	$38.89 - $70.09
Q4 2021	30,656	$2,032	$68.71	$57.94 - $84.83
Q3 2021	48,019	$2,998	$64.75	$57.92 - $86.01
Q2 2021	24,031	$1,990	$74.45	$60.52 - $93.66
Q1 2021	30,119	$1,997	$77.59	$60.64 - $92.60
Q4 2020	32,029	$2,458	$63.95	$42.44 - $86.75
Q3 2020	188,244	$8,106	$43.15	$32.86 - $53.12
Q4 2019	75,857	$4,812	$49.62	$27.11 - $73.72
Q3 2019	7,856	$221	$29.59	$25.68 - $36.80
Q2 2019	413,289	$10,952	$21.95	$17.30 - $28.84
Q1 2019	943,835	$17,319	$16.50	$11.67 - $20.60
Q4 2018	106,941	$1,328	$13.67	$10.41 - $20.31
Q3 2018	272,061	$5,215	$16.41	$12.25 - $22.39
Q1 2018	817,317	$5,893	$6.16	$3.57 - $8.09
Q4 2017	1,016,427	$3,740	$3.71	$3.01 - $4.54
Q3 2017	1,272,138	$5,508	$2.38	$1.48 - $4.42
Q2 2017	1,477,039	$2,393	$1.62	$1.42 - $2.04
Q1 2017	484,330	$896	$1.98	$1.42 - $2.45
Q4 2016	1,177,293	$1,825	$4.26	$1.20 - $7.74
Q3 2016	33,620	$247	$6.48	$5.29 - $8.22
Q2 2016	29,511	$157	$5.71	$4.68 - $6.55