ARROWHEAD PHARMACEUTICALS IN

Ticker: ARWR CUSIP: 04280A100 Class: Common Stock

JANUS HENDERSON GROUP PLC's Holding History (CIK: 0001274173)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 1,280,446 Value ($000) $84,997 Avg Close $49.01 Range $34.38 - $72.36

Q3 2025

Shares 973,567 Value ($000) $33,535 Avg Close $21.98 Range $14.30 - $34.61

Q2 2025

Shares 49,845 Value ($000) $788 Avg Close $14.35 Range $9.57 - $17.49

Q1 2025

Shares 49,845 Value ($000) $689 Avg Close $18.18 Range $12.14 - $21.84

Q4 2024

Shares 49,845 Value ($000) $937 Avg Close $20.59 Range $17.05 - $27.34

Q3 2024

Shares 49,845 Value ($000) $965 Avg Close $24.41 Range $19.07 - $30.41

Q2 2024

Shares 56,845 Value ($000) $1,476 Avg Close $24.57 Range $21.39 - $28.50

Q1 2024

Shares 57,449 Value ($000) $1,641 Avg Close $31.99 Range $27.00 - $39.83

Q4 2023

Shares 47,367 Value ($000) $1,450 Avg Close $26.56 Range $20.67 - $31.68

Q3 2023

Shares 47,458 Value ($000) $1,274 Avg Close $30.63 Range $26.04 - $36.43

Q2 2023

Shares 47,453 Value ($000) $1,692 Avg Close $34.48 Range $24.64 - $42.48

Q1 2023

Shares 642,057 Value ($000) $16,309 Avg Close $31.45 Range $23.09 - $41.03

Q4 2022

Shares 565,908 Value ($000) $22,953 Avg Close $33.13 Range $27.75 - $40.62

Q3 2022

Shares 569,233 Value ($000) $18,813 Avg Close $40.36 Range $29.60 - $48.48

Q2 2022

Shares 571,430 Value ($000) $20,120 Avg Close $37.62 Range $26.81 - $51.11

Q1 2022

Shares 731,564 Value ($000) $33,645 Avg Close $49.51 Range $38.89 - $70.09

Q4 2021

Shares 966,685 Value ($000) $64,090 Avg Close $68.71 Range $57.94 - $84.83

Q3 2021

Shares 960,232 Value ($000) $59,948 Avg Close $64.75 Range $57.92 - $86.01

Q2 2021

Shares 1,141,595 Value ($000) $94,547 Avg Close $74.45 Range $60.52 - $93.66

Q1 2021

Shares 1,140,313 Value ($000) $75,614 Avg Close $77.59 Range $60.64 - $92.60

Q4 2020

Shares 1,145,443 Value ($000) $87,890 Avg Close $63.95 Range $42.44 - $86.75

Q3 2020

Shares 1,158,462 Value ($000) $49,883 Avg Close $43.15 Range $32.86 - $53.12

Q2 2020

Shares 927,799 Value ($000) $40,072 Avg Close $35.29 Range $25.79 - $43.84

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	1,280,446	$84,997	$49.01	$34.38 - $72.36
Q3 2025	973,567	$33,535	$21.98	$14.30 - $34.61
Q2 2025	49,845	$788	$14.35	$9.57 - $17.49
Q1 2025	49,845	$689	$18.18	$12.14 - $21.84
Q4 2024	49,845	$937	$20.59	$17.05 - $27.34
Q3 2024	49,845	$965	$24.41	$19.07 - $30.41
Q2 2024	56,845	$1,476	$24.57	$21.39 - $28.50
Q1 2024	57,449	$1,641	$31.99	$27.00 - $39.83
Q4 2023	47,367	$1,450	$26.56	$20.67 - $31.68
Q3 2023	47,458	$1,274	$30.63	$26.04 - $36.43
Q2 2023	47,453	$1,692	$34.48	$24.64 - $42.48
Q1 2023	642,057	$16,309	$31.45	$23.09 - $41.03
Q4 2022	565,908	$22,953	$33.13	$27.75 - $40.62
Q3 2022	569,233	$18,813	$40.36	$29.60 - $48.48
Q2 2022	571,430	$20,120	$37.62	$26.81 - $51.11
Q1 2022	731,564	$33,645	$49.51	$38.89 - $70.09
Q4 2021	966,685	$64,090	$68.71	$57.94 - $84.83
Q3 2021	960,232	$59,948	$64.75	$57.92 - $86.01
Q2 2021	1,141,595	$94,547	$74.45	$60.52 - $93.66
Q1 2021	1,140,313	$75,614	$77.59	$60.64 - $92.60
Q4 2020	1,145,443	$87,890	$63.95	$42.44 - $86.75
Q3 2020	1,158,462	$49,883	$43.15	$32.86 - $53.12
Q2 2020	927,799	$40,072	$35.29	$25.79 - $43.84