ARVINAS INC

Ticker: ARVN CUSIP: 04335A105 Class: Common Stock

MANUFACTURERS LIFE INSURANCE COMPANY, THE's Holding History (CIK: 0000928047)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 19,747 Value ($000) $234 Avg Close $10.92 Range $8.60 - $14.22

Q3 2025

Shares 22,400 Value ($000) $191 Avg Close $7.58 Range $6.06 - $8.71

Q2 2025

Shares 64,039 Value ($000) $471 Avg Close $7.37 Range $5.90 - $9.68

Q1 2025

Shares 81,537 Value ($000) $572 Avg Close $15.67 Range $6.88 - $21.00

Q4 2024

Shares 89,540 Value ($000) $1,716 Avg Close $24.30 Range $17.37 - $29.61

Q3 2024

Shares 90,406 Value ($000) $2,227 Avg Close $26.11 Range $23.10 - $34.11

Q2 2024

Shares 95,105 Value ($000) $2,532 Avg Close $31.86 Range $23.73 - $41.34

Q1 2024

Shares 119,481 Value ($000) $4,932 Avg Close $43.69 Range $35.42 - $53.08

Q4 2023

Shares 89,228 Value ($000) $3,673 Avg Close $23.38 Range $13.57 - $42.84

Q3 2023

Shares 67,317 Value ($000) $1,322 Avg Close $24.53 Range $19.14 - $28.99

Q2 2023

Shares 61,573 Value ($000) $1,528 Avg Close $25.72 Range $21.21 - $32.20

Q1 2023

Shares 55,510 Value ($000) $1,517 Avg Close $31.59 Range $25.35 - $37.95

Q4 2022

Shares 55,409 Value ($000) $1,903 Avg Close $42.07 Range $31.54 - $57.96

Q3 2022

Shares 49,971 Value ($000) $2,233 Avg Close $48.55 Range $40.93 - $58.58

Q2 2022

Shares 50,403 Value ($000) $2,169 Avg Close $50.18 Range $34.90 - $75.39

Q1 2022

Shares 49,901 Value ($000) $3,253 Avg Close $68.16 Range $58.23 - $82.86

Q4 2021

Shares 23,379 Value ($000) $1,891 Avg Close $81.37 Range $64.00 - $97.33

Q3 2021

Shares 22,327 Value ($000) $1,835 Avg Close $88.38 Range $72.07 - $108.47

Q2 2021

Shares 24,465 Value ($000) $1,884 Avg Close $69.42 Range $56.64 - $84.90

Q1 2021

Shares 20,421 Value ($000) $1,350 Avg Close $76.50 Range $56.59 - $92.77

Q4 2020

Shares 20,831 Value ($000) $1,769 Avg Close $34.48 Range $19.68 - $86.44

Q3 2020

Shares 17,373 Value ($000) $410 Avg Close $28.98 Range $22.38 - $36.86

Q2 2020

Shares 17,727 Value ($000) $566 Avg Close $42.45 Range $29.28 - $61.57

Q1 2020

Shares 13,899 Value ($000) $560 Avg Close $46.77 Range $32.45 - $54.95

Q4 2019

Shares 11,652 Value ($000) $479 Avg Close $29.28 Range $15.19 - $44.97

Q3 2019

Shares 11,870 Value ($000) $270 Avg Close $24.54 Range $21.36 - $28.25

Q2 2019

Shares 11,477 Value ($000) $252 Avg Close $21.02 Range $14.74 - $24.33

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	19,747	$234	$10.92	$8.60 - $14.22
Q3 2025	22,400	$191	$7.58	$6.06 - $8.71
Q2 2025	64,039	$471	$7.37	$5.90 - $9.68
Q1 2025	81,537	$572	$15.67	$6.88 - $21.00
Q4 2024	89,540	$1,716	$24.30	$17.37 - $29.61
Q3 2024	90,406	$2,227	$26.11	$23.10 - $34.11
Q2 2024	95,105	$2,532	$31.86	$23.73 - $41.34
Q1 2024	119,481	$4,932	$43.69	$35.42 - $53.08
Q4 2023	89,228	$3,673	$23.38	$13.57 - $42.84
Q3 2023	67,317	$1,322	$24.53	$19.14 - $28.99
Q2 2023	61,573	$1,528	$25.72	$21.21 - $32.20
Q1 2023	55,510	$1,517	$31.59	$25.35 - $37.95
Q4 2022	55,409	$1,903	$42.07	$31.54 - $57.96
Q3 2022	49,971	$2,233	$48.55	$40.93 - $58.58
Q2 2022	50,403	$2,169	$50.18	$34.90 - $75.39
Q1 2022	49,901	$3,253	$68.16	$58.23 - $82.86
Q4 2021	23,379	$1,891	$81.37	$64.00 - $97.33
Q3 2021	22,327	$1,835	$88.38	$72.07 - $108.47
Q2 2021	24,465	$1,884	$69.42	$56.64 - $84.90
Q1 2021	20,421	$1,350	$76.50	$56.59 - $92.77
Q4 2020	20,831	$1,769	$34.48	$19.68 - $86.44
Q3 2020	17,373	$410	$28.98	$22.38 - $36.86
Q2 2020	17,727	$566	$42.45	$29.28 - $61.57
Q1 2020	13,899	$560	$46.77	$32.45 - $54.95
Q4 2019	11,652	$479	$29.28	$15.19 - $44.97
Q3 2019	11,870	$270	$24.54	$21.36 - $28.25
Q2 2019	11,477	$252	$21.02	$14.74 - $24.33