AVALANCHE BIOTECHNOLOGIES IN

CUSIP: 05337G107 Class: COM

RENAISSANCE TECHNOLOGIES LLC's Holding History (CIK: 0001037389)

Note: Option positions (PUT/CALL) are excluded.

Q1 2016
Shares 278,700 Value ($000) $1,441 Avg Close — Range —
Q4 2015
Shares 82,100 Value ($000) $782 Avg Close — Range —