AVALANCHE BIOTECHNOLOGIES IN

CUSIP: 05337G107 Class: COM

RTW INVESTMENTS, LP's Holding History (CIK: 0001493215)

Note: Option positions (PUT/CALL) are excluded.

Q1 2015
Shares 51,300 Value ($000) $2,079 Avg Close — Range —
Q4 2014
Shares 50,000 Value ($000) $2,700 Avg Close — Range —