RTW INVESTMENTS, LP Diversified Active

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
IRTC	IRHYTHM TECHNOLOGIES INC	1,181,990	$209,732	2.1%	$177.21	0.0%	COM	450056106
APLS	APELLIS PHARMACEUTICALS INC	7,666,764	$192,589	1.9%	$23.46	0.0%	COM	03753U106
RGEN	REPLIGEN CORP	1,064,000	$174,347	1.7%	$156.63	0.0%	COM	759916109
PODD	INSULET CORP	324,600	$92,264	0.9%	$312.66	0.0%	COM	45784P101
CSTL	CASTLE BIOSCIENCES INC	2,115,237	$82,283	0.8%	$32.24	0.0%	COM	14843C105
IMVT	IMMUNOVANT INC	3,177,850	$80,781	0.8%	$22.30	0.0%	COM	45258J102
CELC	CELCUITY INC	550,160	$54,873	0.5%	$82.21	0.0%	COM	15102K100
KOD	KODIAK SCIENCES INC	1,487,933	$41,603	0.4%	$20.48	0.0%	COM	50015M109
ARWR	ARROWHEAD PHARMACEUTICALS IN	584,716	$38,819	0.4%	$49.01	0.0%	COM	04280A100
SVRA	SAVARA INC	5,952,380	$35,893	0.4%	$4.90	0.0%	COM	805111101
EVMN	EVOMMUNE INC	1,283,671	$21,976	0.2%	$18.78	0.0%	COM SHS	30054Y107
KYMR	KYMERA THERAPEUTICS INC	240,000	$18,674	0.2%	$67.53	0.0%	COM	501575104
FLGT	FULGENT GENETICS INC	705,027	$18,521	0.2%	$25.94	0.0%	COM	359664109
HNGE	HINGE HEALTH INC	353,500	$16,420	0.2%	$48.16	0.0%	CL A	433313103
BEAM	BEAM THERAPEUTICS INC	570,394	$15,811	0.2%	$25.51	0.0%	COM	07373V105
TNGX	TANGO THERAPEUTICS INC	1,491,228	$13,212	0.1%	$8.62	0.0%	COM	87583X109
LMRI	LUMEXA IMAGING HOLDINGS INC	650,000	$12,025	0.1%	$18.05	0.0%	COM	550249106
KLRS	KALARIS THERAPEUTICS INC	1,300,000	$10,972	0.1%	$6.39	0.0%	COM	482929106
IQV	IQVIA HLDGS INC	46,000	$10,369	0.1%	$217.58	0.0%	COM	46266C105
—	ATAI BECKLEY NV	2,000,000	$8,180	0.1%	$4.09	—	SHS	N0731H103
CAPR	CAPRICOR THERAPEUTICS INC	250,000	$7,215	0.1%	$13.06	0.0%	COM NEW	14070B309
GPCR	STRUCTURE THERAPEUTICS INC	100,000	$6,955	0.1%	$69.55	—	SPONSORED ADS	86366E106
IVA	INVENTIVA SA	1,298,701	$6,039	0.1%	$4.65	—	ADS	46124U107
CBIO	CRESCENT BIOPHARMA INC.	372,856	$4,422	0.0%	$12.74	0.0%	COM	G2545C104
—	MIND MEDICINE MINDMED INC	300,000	$4,017	0.0%	$13.39	—	COM NEW	60255C885
FDMT	4D MOLECULAR THERAPEUTICS IN	475,737	$3,568	0.0%	$10.14	0.0%	COM	35104E100
MDLN	MEDLINE INC	70,000	$2,940	0.0%	$42.23	0.0%	COM CL A	58507V107
IRON	DISC MEDICINE INC	30,000	$2,382	0.0%	$84.50	0.0%	COM	254604101
ERAS	ERASCA INC	146,651	$546	0.0%	$2.81	0.0%	COM	29479A108

Increased Positions (19)

INSM INSMED INC 8.4%

Value ($000) $842,855 (+89.7%) Shares 4,842,879 (+57.0%) Est. Cost $85.76 Unrealized +112.8%

COGT COGENT BIOSCIENCES INC 2.7%

Value ($000) $269,676 (+441.6%) Shares 7,592,241 (+119.0%) Est. Cost $20.68 Unrealized +35.9%

BLTE BELITE BIO INC 1.1%

Value ($000) $114,425 (+394.8%) Shares 715,332 (+128.9%) Est. Cost $122.41 Unrealized —

TARS TARSUS PHARMACEUTICALS INC 2.7%

Value ($000) $273,096 (+44.6%) Shares 3,335,320 (+5.0%) Est. Cost $28.29 Unrealized +164.0%

SYRE SPYRE THERAPEUTICS INC 1.4%

Value ($000) $136,675 (+125.1%) Shares 4,171,996 (+15.2%) Est. Cost $21.67 Unrealized +20.6%

RDNT RADNET INC 2.8%

Value ($000) $281,012 (+31.0%) Shares 3,938,500 (+39.9%) Est. Cost $55.16 Unrealized +40.0%

STOK STOKE THERAPEUTICS INC 1.8%

Value ($000) $176,057 (+46.2%) Shares 5,546,856 (+8.3%) Est. Cost $22.80 Unrealized +31.8%

ZLAB ZAI LAB LTD 1.2%

Value ($000) $122,757 (+58.1%) Shares 6,959,032 (+203.7%) Est. Cost $22.08 Unrealized —

IMTX IMMATICS N.V 1.2%

Value ($000) $120,050 (+59.8%) Shares 11,433,354 (+29.7%) Est. Cost $10.05 Unrealized +0.4%

REPL REPLIMUNE GROUP INC 0.7%

Value ($000) $69,404 (+159.0%) Shares 7,140,352 (+11.6%) Est. Cost $7.45 Unrealized +14.1%

XNCR XENCOR INC 1.0%

Value ($000) $103,763 (+42.2%) Shares 6,777,461 (+8.9%) Est. Cost $13.91 Unrealized +7.4%

CRNX CRINETICS PHARMACEUTICALS IN 0.6%

Value ($000) $62,904 (+73.1%) Shares 1,351,326 (+54.9%) Est. Cost $36.04 Unrealized +23.5%

ORKA ORUKA THERAPEUTICS INC 0.6%

Value ($000) $62,382 (+66.7%) Shares 2,058,148 (+5.8%) Est. Cost $33.93 Unrealized -17.9%

RAPT RAPT THERAPEUTICS INC 0.6%

Value ($000) $55,451 (+46.2%) Shares 1,637,165 (+11.3%) Est. Cost $10.01 Unrealized +210.1%

WVE WAVE LIFE SCIENCES LTD 0.2%

Value ($000) $22,950 (+248.4%) Shares 1,350,000 (+50.0%) Est. Cost $7.37 Unrealized +37.8%

CGON CG ONCOLOGY INC 0.8%

Value ($000) $83,544 (+21.9%) Shares 2,012,127 (+18.3%) Est. Cost $36.89 Unrealized +12.2%

GHRS GH RESEARCH PLC 0.8%

Value ($000) $75,359 (-5.4%) Shares 5,933,815 (+6.5%) Est. Cost $14.83 Unrealized -8.1%

VSTM VERASTEM INC 0.5%

Value ($000) $50,769 (+6.0%) Shares 6,576,306 (+21.2%) Est. Cost $6.84 Unrealized +30.3%

ALUR ALLURION TECHNOLOGIES INC 0.1%

Value ($000) $7,246 (+39.0%) Shares 5,891,430 (+131.7%) Est. Cost $2.38 Unrealized -29.4%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
INSM	INSMED INC	4,842,879 (+57.0%)	$842,855 (+89.7%)	8.4%	$85.76	+112.8%	COM PAR $.01	457669307
COGT	COGENT BIOSCIENCES INC	7,592,241 (+119.0%)	$269,676 (+441.6%)	2.7%	$20.68	+35.9%	COM	19240Q201
BLTE	BELITE BIO INC	715,332 (+128.9%)	$114,425 (+394.8%)	1.1%	$122.41	—	SPONSORED ADS	07782B104
TARS	TARSUS PHARMACEUTICALS INC	3,335,320 (+5.0%)	$273,096 (+44.6%)	2.7%	$28.29	+164.0%	COM	87650L103
SYRE	SPYRE THERAPEUTICS INC	4,171,996 (+15.2%)	$136,675 (+125.1%)	1.4%	$21.67	+20.6%	COM NEW	00773J202
RDNT	RADNET INC	3,938,500 (+39.9%)	$281,012 (+31.0%)	2.8%	$55.16	+40.0%	COM	750491102
STOK	STOKE THERAPEUTICS INC	5,546,856 (+8.3%)	$176,057 (+46.2%)	1.8%	$22.80	+31.8%	COM	86150R107
ZLAB	ZAI LAB LTD	6,959,032 (+203.7%)	$122,757 (+58.1%)	1.2%	$22.08	—	ADR	98887Q104
IMTX	IMMATICS N.V	11,433,354 (+29.7%)	$120,050 (+59.8%)	1.2%	$10.05	+0.4%	SHS	N44445109
REPL	REPLIMUNE GROUP INC	7,140,352 (+11.6%)	$69,404 (+159.0%)	0.7%	$7.45	+14.1%	COM	76029N106
XNCR	XENCOR INC	6,777,461 (+8.9%)	$103,763 (+42.2%)	1.0%	$13.91	+7.4%	COM	98401F105
CRNX	CRINETICS PHARMACEUTICALS IN	1,351,326 (+54.9%)	$62,904 (+73.1%)	0.6%	$36.04	+23.5%	COM	22663K107
ORKA	ORUKA THERAPEUTICS INC	2,058,148 (+5.8%)	$62,382 (+66.7%)	0.6%	$33.93	-17.9%	COM	687604108
RAPT	RAPT THERAPEUTICS INC	1,637,165 (+11.3%)	$55,451 (+46.2%)	0.6%	$10.01	+210.1%	COM NEW	75382E208
WVE	WAVE LIFE SCIENCES LTD	1,350,000 (+50.0%)	$22,950 (+248.4%)	0.2%	$7.37	+37.8%	SHS	Y95308105
CGON	CG ONCOLOGY INC	2,012,127 (+18.3%)	$83,544 (+21.9%)	0.8%	$36.89	+12.2%	COM	156944100
GHRS	GH RESEARCH PLC	5,933,815 (+6.5%)	$75,359 (-5.4%)	0.8%	$14.83	-8.1%	ORDINARY SHARES	G3855L106
VSTM	VERASTEM INC	6,576,306 (+21.2%)	$50,769 (+6.0%)	0.5%	$6.84	+30.3%	COM NEW	92337C203
ALUR	ALLURION TECHNOLOGIES INC	5,891,430 (+131.7%)	$7,246 (+39.0%)	0.1%	$2.38	-29.4%	COMMON STOCK	02008G201

Exited Positions (12)

RNA AVIDITY BIOSCIENCES INC 5.0%

Value ($000) $495,514 Shares 11,372,829 Est. Cost $27.49 Unrealized +135.0%

— AKERO THERAPEUTICS INC 2.6%

Value ($000) $260,075 Shares 5,477,561 Est. Cost $26.03 Unrealized —

— MERUS N V 1.9%

Value ($000) $190,680 Shares 2,025,277 Est. Cost $34.07 Unrealized —

DGX QUEST DIAGNOSTICS INC 0.5%

Value ($000) $47,645 Shares 250,000 Est. Cost $170.08 Unrealized +7.0%

LENZ LENZ THERAPEUTICS INC 0.4%

Value ($000) $40,217 Shares 863,389 Est. Cost $20.79 Unrealized +40.2%

DYN DYNE THERAPEUTICS INC 0.4%

Value ($000) $36,566 Shares 2,890,567 Est. Cost $20.42 Unrealized -7.3%

ABVX ABIVAX SA 0.3%

Value ($000) $29,715 Shares 350,000 Est. Cost $84.90 Unrealized —

GEHC GE HEALTHCARE TECHNOLOGIES I 0.3%

Value ($000) $29,552 Shares 393,500 Est. Cost $83.06 Unrealized -6.2%

ALEC ALECTOR INC 0.2%

Value ($000) $20,693 Shares 6,990,806 Est. Cost $2.20 Unrealized -19.5%

CTMX CYTOMX THERAPEUTICS INC 0.1%

Value ($000) $11,042 Shares 3,461,500 Est. Cost $1.61 Unrealized +135.7%

PEPG PEPGEN INC 0.1%

Value ($000) $6,930 Shares 1,500,000 Est. Cost $1.61 Unrealized +222.0%

ADGM ADAGIO MED HLDGS INC 0.0%

Value ($000) $406 Shares 209,361 Est. Cost $4.76 Unrealized -75.1%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
RNA	AVIDITY BIOSCIENCES INC	11,372,829	$495,514	5.0%	$27.49	+135.0%	—	05370A108
—	AKERO THERAPEUTICS INC	5,477,561	$260,075	2.6%	$26.03	—	—	00973Y108
—	MERUS N V	2,025,277	$190,680	1.9%	$34.07	—	—	N5749R100
DGX	QUEST DIAGNOSTICS INC	250,000	$47,645	0.5%	$170.08	+7.0%	—	74834L100
LENZ	LENZ THERAPEUTICS INC	863,389	$40,217	0.4%	$20.79	+40.2%	—	52635N103
DYN	DYNE THERAPEUTICS INC	2,890,567	$36,566	0.4%	$20.42	-7.3%	—	26818M108
ABVX	ABIVAX SA	350,000	$29,715	0.3%	$84.90	—	—	00370M103
GEHC	GE HEALTHCARE TECHNOLOGIES I	393,500	$29,552	0.3%	$83.06	-6.2%	—	36266G107
ALEC	ALECTOR INC	6,990,806	$20,693	0.2%	$2.20	-19.5%	—	014442107
CTMX	CYTOMX THERAPEUTICS INC	3,461,500	$11,042	0.1%	$1.61	+135.7%	—	23284F105
PEPG	PEPGEN INC	1,500,000	$6,930	0.1%	$1.61	+222.0%	—	713317105
ADGM	ADAGIO MED HLDGS INC	209,361	$406	0.0%	$4.76	-75.1%	—	00534B100

Decreased Positions (12)

QURE UNIQURE NV 0.9%

Value ($000) $88,815 (-65.6%) Shares 3,711,462 (-16.1%) Est. Cost $12.98 Unrealized +197.4%

SYK STRYKER CORPORATION 0.9%

Value ($000) $86,110 (-52.5%) Shares 245,000 (-50.0%) Est. Cost $348.93 Unrealized +4.2%

PTGX PROTAGONIST THERAPEUTICS INC 4.4%

Value ($000) $441,858 (+15.6%) Shares 5,059,053 (-12.1%) Est. Cost $23.47 Unrealized +248.8%

ISRG INTUITIVE SURGICAL INC 0.6%

Value ($000) $57,331 (-36.7%) Shares 101,228 (-50.0%) Est. Cost $553.02 Unrealized -3.7%

RARE ULTRAGENYX PHARMACEUTICAL IN 0.7%

Value ($000) $69,003 (-29.6%) Shares 3,000,139 (-7.9%) Est. Cost $40.76 Unrealized -19.3%

AXSM AXSOME THERAPEUTICS INC 1.6%

Value ($000) $162,185 (+19.4%) Shares 888,001 (-20.6%) Est. Cost $56.00 Unrealized +149.3%

NTRA NATERA INC 3.4%

Value ($000) $343,635 (+6.7%) Shares 1,500,000 (-25.0%) Est. Cost $42.76 Unrealized +387.8%

CRVS CORVUS PHARMACEUTICALS INC 0.0%

Value ($000) $3,447 (-82.5%) Shares 447,607 (-83.3%) Est. Cost $7.47 Unrealized +5.6%

XGN EXAGEN INC 0.0%

Value ($000) $4,806 (-74.2%) Shares 790,462 (-53.4%) Est. Cost $11.21 Unrealized -18.8%

CNTA CENTESSA PHARMACEUTICALS PLC 0.4%

Value ($000) $44,789 (-19.4%) Shares 1,790,837 (-21.9%) Est. Cost $16.90 Unrealized —

BBNX BETA BIONICS INC 0.8%

Value ($000) $76,175 (+16.2%) Shares 2,500,000 (-24.2%) Est. Cost $18.64 Unrealized +43.2%

TSHA TAYSHA GENE THERAPIES INC 0.9%

Value ($000) $90,191 (+13.2%) Shares 16,398,297 (-32.7%) Est. Cost $1.88 Unrealized +158.9%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
QURE	UNIQURE NV	3,711,462 (-16.1%)	$88,815 (-65.6%)	0.9%	$12.98	+197.4%	SHS	N90064101
SYK	STRYKER CORPORATION	245,000 (-50.0%)	$86,110 (-52.5%)	0.9%	$348.93	+4.2%	COM	863667101
PTGX	PROTAGONIST THERAPEUTICS INC	5,059,053 (-12.1%)	$441,858 (+15.6%)	4.4%	$23.47	+248.8%	COM	74366E102
ISRG	INTUITIVE SURGICAL INC	101,228 (-50.0%)	$57,331 (-36.7%)	0.6%	$553.02	-3.7%	COM NEW	46120E602
RARE	ULTRAGENYX PHARMACEUTICAL IN	3,000,139 (-7.9%)	$69,003 (-29.6%)	0.7%	$40.76	-19.3%	COM	90400D108
AXSM	AXSOME THERAPEUTICS INC	888,001 (-20.6%)	$162,185 (+19.4%)	1.6%	$56.00	+149.3%	COM	05464T104
NTRA	NATERA INC	1,500,000 (-25.0%)	$343,635 (+6.7%)	3.4%	$42.76	+387.8%	COM	632307104
CRVS	CORVUS PHARMACEUTICALS INC	447,607 (-83.3%)	$3,447 (-82.5%)	0.0%	$7.47	+5.6%	COM	221015100
XGN	EXAGEN INC	790,462 (-53.4%)	$4,806 (-74.2%)	0.0%	$11.21	-18.8%	COM	30068X103
CNTA	CENTESSA PHARMACEUTICALS PLC	1,790,837 (-21.9%)	$44,789 (-19.4%)	0.4%	$16.90	—	SPONSORED ADS	152309100
BBNX	BETA BIONICS INC	2,500,000 (-24.2%)	$76,175 (+16.2%)	0.8%	$18.64	+43.2%	COM	08659B102
TSHA	TAYSHA GENE THERAPIES INC	16,398,297 (-32.7%)	$90,191 (+13.2%)	0.9%	$1.88	+158.9%	COM SHS	877619106

Unchanged Positions (31)

MDGL MADRIGAL PHARMACEUTICALS INC 11.6%

Value ($000) $1,161,004 Shares 1,993,687 Est. Cost $231.65 Unrealized +120.5%

PTCT PTC THERAPEUTICS INC 5.9%

Value ($000) $588,418 Shares 7,746,415 Est. Cost $38.50 Unrealized +88.8%

APGE APOGEE THERAPEUTICS INC 2.1%

Value ($000) $204,709 Shares 2,712,097 Est. Cost $27.01 Unrealized +133.2%

ESTA ESTABLISHMENT LABS HLDGS INC 1.9%

Value ($000) $188,674 Shares 2,588,831 Est. Cost $28.18 Unrealized +114.3%

ARGX ARGENX SE 5.7%

Value ($000) $566,377 Shares 673,497 Est. Cost $351.97 Unrealized —

GH GUARDANT HEALTH INC 1.5%

Value ($000) $151,273 Shares 1,481,033 Est. Cost $48.77 Unrealized +83.4%

PEN PENUMBRA INC 2.7%

Value ($000) $269,403 Shares 866,499 Est. Cost $247.59 Unrealized +11.6%

ACAD ACADIA PHARMACEUTICALS INC 1.9%

Value ($000) $190,830 Shares 7,144,524 Est. Cost $21.24 Unrealized +12.5%

CYTK CYTOKINETICS INC 1.7%

Value ($000) $172,902 Shares 2,721,158 Est. Cost $29.14 Unrealized +113.4%

URGN UROGEN PHARMA LTD 1.1%

Value ($000) $106,418 Shares 4,543,895 Est. Cost $14.29 Unrealized +51.8%

OBIO ORCHESTRA BIOMED HLDGS INC 0.3%

Value ($000) $34,470 Shares 8,306,063 Est. Cost $10.12 Unrealized -60.1%

MASI MASIMO CORP 0.9%

Value ($000) $88,869 Shares 683,294 Est. Cost $166.52 Unrealized -14.0%

CMPS COMPASS PATHWAYS PLC 0.6%

Value ($000) $60,426 Shares 8,757,390 Est. Cost $3.33 Unrealized —

JBIO JADE BIOSCIENCES INC 0.2%

Value ($000) $22,362 Shares 1,449,273 Est. Cost $33.31 Unrealized -64.8%

IMCR IMMUNOCORE HLDGS PLC 1.7%

Value ($000) $169,031 Shares 4,869,798 Est. Cost $43.23 Unrealized —

CGEM CULLINAN THERAPEUTICS INC 0.2%

Value ($000) $17,657 Shares 1,705,960 Est. Cost $19.93 Unrealized -54.7%

AQST AQUESTIVE THERAPEUTICS INC 0.4%

Value ($000) $40,375 Shares 6,250,000 Est. Cost $4.32 Unrealized +44.1%

CMPX COMPASS THERAPEUTICS INC 0.1%

Value ($000) $13,425 Shares 2,500,000 Est. Cost $3.16 Unrealized +46.2%

NGNE NEUROGENE INC 0.3%

Value ($000) $28,067 Shares 1,362,456 Est. Cost $34.49 Unrealized -27.8%

RCKT ROCKET PHARMACEUTICALS INC 0.6%

Value ($000) $62,084 Shares 17,687,772 Est. Cost $17.75 Unrealized -80.7%

TEM TEMPUS AI INC 0.1%

Value ($000) $11,810 Shares 200,000 Est. Cost $53.98 Unrealized +44.9%

ALKS ALKERMES PLC 0.5%

Value ($000) $46,793 Shares 1,672,356 Est. Cost $27.15 Unrealized +10.3%

HTFL HEARTFLOW INC 0.1%

Value ($000) $14,429 Shares 495,000 Est. Cost $32.24 Unrealized -0.1%

PCSC PERCEPTIVE CAP SOLUTIONS COR 0.1%

Value ($000) $9,675 Shares 742,500 Est. Cost $10.07 Unrealized +11.9%

LRMR LARIMAR THERAPEUTICS INC 0.1%

Value ($000) $11,906 Shares 3,125,000 Est. Cost $3.75 Unrealized +3.7%

TENX TENAX THERAPEUTICS INC 0.0%

Value ($000) $4,612 Shares 378,346 Est. Cost $6.41 Unrealized +35.6%

NBIX NEUROCRINE BIOSCIENCES INC 1.5%

Value ($000) $150,634 Shares 1,062,072 Est. Cost $114.68 Unrealized +26.3%

OMDA OMADA HEALTH INC 0.0%

Value ($000) $3,156 Shares 200,000 Est. Cost $17.31 Unrealized +17.2%

IMA IMAGENEBIO INC 0.0%

Value ($000) $2,308 Shares 334,445 Est. Cost $13.25 Unrealized -44.1%

MIST MILESTONE PHARMACEUTICALS IN 0.1%

Value ($000) $5,062 Shares 2,506,102 Est. Cost $20.06 Unrealized -89.3%

RCKTW ROCKET PHARMACEUTICALS INC 0.0%

Value ($000) $9 Shares 350,000 Est. Cost $0.11 Unrealized —

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
MDGL	MADRIGAL PHARMACEUTICALS INC	1,993,687	$1,161,004	11.6%	$231.65	+120.5%	COM	558868105
PTCT	PTC THERAPEUTICS INC	7,746,415	$588,418	5.9%	$38.50	+88.8%	COM	69366J200
APGE	APOGEE THERAPEUTICS INC	2,712,097	$204,709	2.1%	$27.01	+133.2%	COM	03770N101
ESTA	ESTABLISHMENT LABS HLDGS INC	2,588,831	$188,674	1.9%	$28.18	+114.3%	COM	G31249108
ARGX	ARGENX SE	673,497	$566,377	5.7%	$351.97	—	SPONSORED ADR	04016X101
GH	GUARDANT HEALTH INC	1,481,033	$151,273	1.5%	$48.77	+83.4%	COM	40131M109
PEN	PENUMBRA INC	866,499	$269,403	2.7%	$247.59	+11.6%	COM	70975L107
ACAD	ACADIA PHARMACEUTICALS INC	7,144,524	$190,830	1.9%	$21.24	+12.5%	COM	004225108
CYTK	CYTOKINETICS INC	2,721,158	$172,902	1.7%	$29.14	+113.4%	COM NEW	23282W605
URGN	UROGEN PHARMA LTD	4,543,895	$106,418	1.1%	$14.29	+51.8%	COM	M96088105
OBIO	ORCHESTRA BIOMED HLDGS INC	8,306,063	$34,470	0.3%	$10.12	-60.1%	COM	68572M106
MASI	MASIMO CORP	683,294	$88,869	0.9%	$166.52	-14.0%	COM	574795100
CMPS	COMPASS PATHWAYS PLC	8,757,390	$60,426	0.6%	$3.33	—	SPONSORED ADS	20451W101
JBIO	JADE BIOSCIENCES INC	1,449,273	$22,362	0.2%	$33.31	-64.8%	COM NEW	008064206
IMCR	IMMUNOCORE HLDGS PLC	4,869,798	$169,031	1.7%	$43.23	—	ADS	45258D105
CGEM	CULLINAN THERAPEUTICS INC	1,705,960	$17,657	0.2%	$19.93	-54.7%	COM	230031106
AQST	AQUESTIVE THERAPEUTICS INC	6,250,000	$40,375	0.4%	$4.32	+44.1%	COM	03843E104
CMPX	COMPASS THERAPEUTICS INC	2,500,000	$13,425	0.1%	$3.16	+46.2%	COM	20454B104
NGNE	NEUROGENE INC	1,362,456	$28,067	0.3%	$34.49	-27.8%	COM	64135M105
RCKT	ROCKET PHARMACEUTICALS INC	17,687,772	$62,084	0.6%	$17.75	-80.7%	COM	77313F106
TEM	TEMPUS AI INC	200,000	$11,810	0.1%	$53.98	+44.9%	CL A	88023B103
ALKS	ALKERMES PLC	1,672,356	$46,793	0.5%	$27.15	+10.3%	SHS	G01767105
HTFL	HEARTFLOW INC	495,000	$14,429	0.1%	$32.24	-0.1%	COM	42238D107
PCSC	PERCEPTIVE CAP SOLUTIONS COR	742,500	$9,675	0.1%	$10.07	+11.9%	CL A ORD SHS	G70077105
LRMR	LARIMAR THERAPEUTICS INC	3,125,000	$11,906	0.1%	$3.75	+3.7%	COM	517125100
TENX	TENAX THERAPEUTICS INC	378,346	$4,612	0.0%	$6.41	+35.6%	COM NEW	88032L605
NBIX	NEUROCRINE BIOSCIENCES INC	1,062,072	$150,634	1.5%	$114.68	+26.3%	COM	64125C109
OMDA	OMADA HEALTH INC	200,000	$3,156	0.0%	$17.31	+17.2%	COM	68170A108
IMA	IMAGENEBIO INC	334,445	$2,308	0.0%	$13.25	-44.1%	COM	45175G207
MIST	MILESTONE PHARMACEUTICALS IN	2,506,102	$5,062	0.1%	$20.06	-89.3%	COM	59935V107
RCKTW	ROCKET PHARMACEUTICALS INC	350,000	$9	0.0%	$0.11	—	*W EXP 09/02/202	77313F114