AXSOME THERAPEUTICS INC

Ticker: AXSM CUSIP: 05464T104 Class: Common Stock

GREAT LAKES ADVISORS, LLC's Holding History (CIK: 0001078013)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 6,765 Value ($000) $1,236 Avg Close $139.61 Range $117.30 - $184.40

Q3 2025

Shares 6,676 Value ($000) $811 Avg Close $112.64 Range $96.09 - $130.00

Q2 2025

Shares 6,370 Value ($000) $665 Avg Close $105.89 Range $86.99 - $120.00

Q1 2025

Shares 7,193 Value ($000) $839 Avg Close $113.93 Range $79.19 - $139.13

Q4 2024

Shares 13,508 Value ($000) $1,143 Avg Close $91.96 Range $75.56 - $105.00

Q3 2024

Shares 16,728 Value ($000) $1,503 Avg Close $87.29 Range $72.21 - $97.00

Q2 2024

Shares 12,141 Value ($000) $977 Avg Close $74.04 Range $64.11 - $80.98

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	6,765	$1,236	$139.61	$117.30 - $184.40
Q3 2025	6,676	$811	$112.64	$96.09 - $130.00
Q2 2025	6,370	$665	$105.89	$86.99 - $120.00
Q1 2025	7,193	$839	$113.93	$79.19 - $139.13
Q4 2024	13,508	$1,143	$91.96	$75.56 - $105.00
Q3 2024	16,728	$1,503	$87.29	$72.21 - $97.00
Q2 2024	12,141	$977	$74.04	$64.11 - $80.98