AXSOME THERAPEUTICS INC

Ticker: AXSM CUSIP: 05464T104 Class: Common Stock

CANADA PENSION PLAN INVESTMENT BOARD's Holding History (CIK: 0001283718)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 103,200 Value ($000) $18,848 Avg Close $139.61 Range $117.30 - $184.40

Q3 2025

Shares 64,400 Value ($000) $7,821 Avg Close $112.64 Range $96.09 - $130.00

Q2 2025

Shares 72,300 Value ($000) $7,547 Avg Close $105.89 Range $86.99 - $120.00

Q1 2025

Shares 44,500 Value ($000) $5,190 Avg Close $113.93 Range $79.19 - $139.13

Q4 2024

Shares 4,100 Value ($000) $347 Avg Close $91.96 Range $75.56 - $105.00

Q2 2020

Shares 2,100 Value ($000) $173 Avg Close $76.97 Range $49.12 - $109.53

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	103,200	$18,848	$139.61	$117.30 - $184.40
Q3 2025	64,400	$7,821	$112.64	$96.09 - $130.00
Q2 2025	72,300	$7,547	$105.89	$86.99 - $120.00
Q1 2025	44,500	$5,190	$113.93	$79.19 - $139.13
Q4 2024	4,100	$347	$91.96	$75.56 - $105.00
Q2 2020	2,100	$173	$76.97	$49.12 - $109.53