AXSOME THERAPEUTICS INC

Ticker: AXSM CUSIP: 05464T104 Class: Common Stock

MARSHALL WACE, LLP's Holding History (CIK: 0001318757)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 320,568 Value ($000) $58,549 Avg Close $139.61 Range $117.30 - $184.40

Q3 2025

Shares 378,024 Value ($000) $45,911 Avg Close $112.64 Range $96.09 - $130.00

Q2 2025

Shares 56,716 Value ($000) $5,921 Avg Close $105.89 Range $86.99 - $120.00

Q1 2025

Shares 68,696 Value ($000) $8,012 Avg Close $113.93 Range $79.19 - $139.13

Q4 2024

Shares 127,097 Value ($000) $10,754 Avg Close $91.96 Range $75.56 - $105.00

Q3 2023

Shares 59,248 Value ($000) $4,141 Avg Close $74.75 Range $67.52 - $83.30

Q2 2023

Shares 191,511 Value ($000) $13,762 Avg Close $73.77 Range $56.75 - $91.29

Q1 2023

Shares 7,121 Value ($000) $439 Avg Close $65.70 Range $53.71 - $77.70

Q2 2022

Shares 27,393 Value ($000) $1,049 Avg Close $31.63 Range $20.63 - $47.40

Q1 2021

Shares 23,374 Value ($000) $1,323 Avg Close $70.34 Range $55.30 - $82.98

Q1 2020

Shares 79,454 Value ($000) $4,674 Avg Close $81.48 Range $35.44 - $104.79

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	320,568	$58,549	$139.61	$117.30 - $184.40
Q3 2025	378,024	$45,911	$112.64	$96.09 - $130.00
Q2 2025	56,716	$5,921	$105.89	$86.99 - $120.00
Q1 2025	68,696	$8,012	$113.93	$79.19 - $139.13
Q4 2024	127,097	$10,754	$91.96	$75.56 - $105.00
Q3 2023	59,248	$4,141	$74.75	$67.52 - $83.30
Q2 2023	191,511	$13,762	$73.77	$56.75 - $91.29
Q1 2023	7,121	$439	$65.70	$53.71 - $77.70
Q2 2022	27,393	$1,049	$31.63	$20.63 - $47.40
Q1 2021	23,374	$1,323	$70.34	$55.30 - $82.98
Q1 2020	79,454	$4,674	$81.48	$35.44 - $104.79