AXSOME THERAPEUTICS INC

Ticker: AXSM CUSIP: 05464T104 Class: Common Stock

Brevan Howard Capital Management LP's Holding History (CIK: 0001512857)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 1,238 Value ($000) $226 Avg Close $139.61 Range $117.30 - $184.40

Q3 2025

Shares 7,334 Value ($000) $891 Avg Close $112.64 Range $96.09 - $130.00

Q2 2025

Shares 14,782 Value ($000) $1,543 Avg Close $105.89 Range $86.99 - $120.00

Q4 2024

Shares 38,748 Value ($000) $3,278 Avg Close $91.96 Range $75.56 - $105.00

Q3 2024

Shares 14,355 Value ($000) $1,290 Avg Close $87.29 Range $72.21 - $97.00

Q2 2024

Shares 4,782 Value ($000) $385 Avg Close $74.04 Range $64.11 - $80.98

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	1,238	$226	$139.61	$117.30 - $184.40
Q3 2025	7,334	$891	$112.64	$96.09 - $130.00
Q2 2025	14,782	$1,543	$105.89	$86.99 - $120.00
Q4 2024	38,748	$3,278	$91.96	$75.56 - $105.00
Q3 2024	14,355	$1,290	$87.29	$72.21 - $97.00
Q2 2024	4,782	$385	$74.04	$64.11 - $80.98