AXSOME THERAPEUTICS INC

Ticker: AXSM CUSIP: 05464T104 Class: Common Stock

MetLife Investment Management, LLC's Holding History (CIK: 0001529735)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 164,871 Value ($000) $30,112 Avg Close $139.61 Range $117.30 - $184.40

Q3 2025

Shares 197,318 Value ($000) $23,964 Avg Close $112.64 Range $96.09 - $130.00

Q2 2025

Shares 184,164 Value ($000) $19,225 Avg Close $105.89 Range $86.99 - $120.00

Q1 2025

Shares 178,955 Value ($000) $20,872 Avg Close $113.93 Range $79.19 - $139.13

Q4 2024

Shares 22,277 Value ($000) $1,885 Avg Close $91.96 Range $75.56 - $105.00

Q3 2024

Shares 21,045 Value ($000) $1,891 Avg Close $87.29 Range $72.21 - $97.00

Q2 2024

Shares 21,045 Value ($000) $1,694 Avg Close $74.04 Range $64.11 - $80.98

Q1 2024

Shares 18,503 Value ($000) $1,477 Avg Close $83.94 Range $68.59 - $98.40

Q4 2023

Shares 18,503 Value ($000) $1,473 Avg Close $66.86 Range $55.02 - $84.24

Q3 2023

Shares 18,503 Value ($000) $1,293 Avg Close $74.75 Range $67.52 - $83.30

Q2 2023

Shares 17,221 Value ($000) $1,238 Avg Close $73.77 Range $56.75 - $91.29

Q1 2023

Shares 16,900 Value ($000) $1,042 Avg Close $65.70 Range $53.71 - $77.70

Q4 2022

Shares 16,900 Value ($000) $1,303 Avg Close $59.77 Range $38.87 - $82.00

Q3 2022

Shares 16,342 Value ($000) $729 Avg Close $49.97 Range $35.16 - $71.98

Q2 2022

Shares 17,348 Value ($000) $664 Avg Close $31.63 Range $20.63 - $47.40

Q1 2022

Shares 17,348 Value ($000) $718 Avg Close $31.00 Range $21.85 - $41.95

Q4 2021

Shares 10,909 Value ($000) $412 Avg Close $36.79 Range $29.60 - $44.83

Q3 2021

Shares 10,909 Value ($000) $360 Avg Close $38.97 Range $19.38 - $68.74

Q2 2021

Shares 10,909 Value ($000) $736 Avg Close $60.01 Range $50.05 - $74.10

Q1 2021

Shares 10,909 Value ($000) $618 Avg Close $70.34 Range $55.30 - $82.98

Q4 2020

Shares 10,909 Value ($000) $889 Avg Close $74.78 Range $65.00 - $87.24

Q3 2020

Shares 12,312 Value ($000) $877 Avg Close $77.92 Range $65.25 - $90.00

Q2 2020

Shares 12,312 Value ($000) $1,013 Avg Close $76.97 Range $49.12 - $109.53

Q1 2020

Shares 11,632 Value ($000) $684 Avg Close $81.48 Range $35.44 - $104.79

Q4 2019

Shares 10,670 Value ($000) $1,103 Avg Close $40.39 Range $13.64 - $109.94

Q3 2019

Shares 11,697 Value ($000) $237 Avg Close $25.70 Range $20.10 - $30.50

Q2 2019

Shares 11,697 Value ($000) $301 Avg Close $20.04 Range $12.76 - $26.45

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	164,871	$30,112	$139.61	$117.30 - $184.40
Q3 2025	197,318	$23,964	$112.64	$96.09 - $130.00
Q2 2025	184,164	$19,225	$105.89	$86.99 - $120.00
Q1 2025	178,955	$20,872	$113.93	$79.19 - $139.13
Q4 2024	22,277	$1,885	$91.96	$75.56 - $105.00
Q3 2024	21,045	$1,891	$87.29	$72.21 - $97.00
Q2 2024	21,045	$1,694	$74.04	$64.11 - $80.98
Q1 2024	18,503	$1,477	$83.94	$68.59 - $98.40
Q4 2023	18,503	$1,473	$66.86	$55.02 - $84.24
Q3 2023	18,503	$1,293	$74.75	$67.52 - $83.30
Q2 2023	17,221	$1,238	$73.77	$56.75 - $91.29
Q1 2023	16,900	$1,042	$65.70	$53.71 - $77.70
Q4 2022	16,900	$1,303	$59.77	$38.87 - $82.00
Q3 2022	16,342	$729	$49.97	$35.16 - $71.98
Q2 2022	17,348	$664	$31.63	$20.63 - $47.40
Q1 2022	17,348	$718	$31.00	$21.85 - $41.95
Q4 2021	10,909	$412	$36.79	$29.60 - $44.83
Q3 2021	10,909	$360	$38.97	$19.38 - $68.74
Q2 2021	10,909	$736	$60.01	$50.05 - $74.10
Q1 2021	10,909	$618	$70.34	$55.30 - $82.98
Q4 2020	10,909	$889	$74.78	$65.00 - $87.24
Q3 2020	12,312	$877	$77.92	$65.25 - $90.00
Q2 2020	12,312	$1,013	$76.97	$49.12 - $109.53
Q1 2020	11,632	$684	$81.48	$35.44 - $104.79
Q4 2019	10,670	$1,103	$40.39	$13.64 - $109.94
Q3 2019	11,697	$237	$25.70	$20.10 - $30.50
Q2 2019	11,697	$301	$20.04	$12.76 - $26.45