AXSOME THERAPEUTICS INC

Ticker: AXSM CUSIP: 05464T104 Class: Common Stock

Assenagon Asset Management S.A.'s Holding History (CIK: 0001546007)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 467,982 Value ($000) $85,472 Avg Close $139.61 Range $117.30 - $184.40

Q3 2025

Shares 294,771 Value ($000) $35,800 Avg Close $112.64 Range $96.09 - $130.00

Q2 2025

Shares 180,960 Value ($000) $18,890 Avg Close $105.89 Range $86.99 - $120.00

Q1 2025

Shares 627,418 Value ($000) $73,176 Avg Close $113.93 Range $79.19 - $139.13

Q4 2024

Shares 3,701 Value ($000) $313 Avg Close $91.96 Range $75.56 - $105.00

Q3 2024

Shares 4,483 Value ($000) $403 Avg Close $87.29 Range $72.21 - $97.00

Q2 2024

Shares 33,969 Value ($000) $2,735 Avg Close $74.04 Range $64.11 - $80.98

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	467,982	$85,472	$139.61	$117.30 - $184.40
Q3 2025	294,771	$35,800	$112.64	$96.09 - $130.00
Q2 2025	180,960	$18,890	$105.89	$86.99 - $120.00
Q1 2025	627,418	$73,176	$113.93	$79.19 - $139.13
Q4 2024	3,701	$313	$91.96	$75.56 - $105.00
Q3 2024	4,483	$403	$87.29	$72.21 - $97.00
Q2 2024	33,969	$2,735	$74.04	$64.11 - $80.98