AXSOME THERAPEUTICS INC

Ticker: AXSM CUSIP: 05464T104 Class: Common Stock

JANE STREET GROUP, LLC's Holding History (CIK: 0001595888)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 137,283 Value ($000) $25,073 Avg Close $139.61 Range $117.30 - $184.40

Q3 2025

Shares 130,845 Value ($000) $15,891 Avg Close $112.64 Range $96.09 - $130.00

Q1 2025

Shares 90,141 Value ($000) $10,513 Avg Close $113.93 Range $79.19 - $139.13

Q4 2024

Shares 78,449 Value ($000) $6,638 Avg Close $91.96 Range $75.56 - $105.00

Q3 2024

Shares 130,097 Value ($000) $11,692 Avg Close $87.29 Range $72.21 - $97.00

Q2 2024

Shares 168,434 Value ($000) $13,559 Avg Close $74.04 Range $64.11 - $80.98

Q1 2024

Shares 199,079 Value ($000) $15,887 Avg Close $83.94 Range $68.59 - $98.40

Q4 2023

Shares 92,831 Value ($000) $7,388 Avg Close $66.86 Range $55.02 - $84.24

Q3 2023

Shares 125,581 Value ($000) $8,777 Avg Close $74.75 Range $67.52 - $83.30

Q2 2023

Shares 275,902 Value ($000) $19,826 Avg Close $73.77 Range $56.75 - $91.29

Q1 2023

Shares 21,744 Value ($000) $1,341 Avg Close $65.70 Range $53.71 - $77.70

Q4 2022

Shares 175,899 Value ($000) $13,567 Avg Close $59.77 Range $38.87 - $82.00

Q3 2022

Shares 182,870 Value ($000) $8,159 Avg Close $49.97 Range $35.16 - $71.98

Q2 2022

Shares 41,895 Value ($000) $1,604 Avg Close $31.63 Range $20.63 - $47.40

Q1 2022

Shares 40,559 Value ($000) $1,679 Avg Close $31.00 Range $21.85 - $41.95

Q4 2021

Shares 398,794 Value ($000) $15,067 Avg Close $36.79 Range $29.60 - $44.83

Q3 2021

Shares 293,332 Value ($000) $9,668 Avg Close $38.97 Range $19.38 - $68.74

Q2 2021

Shares 102,711 Value ($000) $6,929 Avg Close $60.01 Range $50.05 - $74.10

Q1 2021

Shares 92,172 Value ($000) $5,219 Avg Close $70.34 Range $55.30 - $82.98

Q4 2020

Shares 72,254 Value ($000) $5,887 Avg Close $74.78 Range $65.00 - $87.24

Q3 2020

Shares 179,255 Value ($000) $12,772 Avg Close $77.92 Range $65.25 - $90.00

Q2 2020

Shares 60,039 Value ($000) $4,939 Avg Close $76.97 Range $49.12 - $109.53

Q1 2020

Shares 110,160 Value ($000) $6,481 Avg Close $81.48 Range $35.44 - $104.79

Q4 2019

Shares 167,656 Value ($000) $17,329 Avg Close $40.39 Range $13.64 - $109.94

Q3 2019

Shares 12,450 Value ($000) $252 Avg Close $25.70 Range $20.10 - $30.50

Q2 2019

Shares 12,058 Value ($000) $310 Avg Close $20.04 Range $12.76 - $26.45

Q1 2019

Shares 19,150 Value ($000) $273 Avg Close $9.29 Range $2.52 - $16.80

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	137,283	$25,073	$139.61	$117.30 - $184.40
Q3 2025	130,845	$15,891	$112.64	$96.09 - $130.00
Q1 2025	90,141	$10,513	$113.93	$79.19 - $139.13
Q4 2024	78,449	$6,638	$91.96	$75.56 - $105.00
Q3 2024	130,097	$11,692	$87.29	$72.21 - $97.00
Q2 2024	168,434	$13,559	$74.04	$64.11 - $80.98
Q1 2024	199,079	$15,887	$83.94	$68.59 - $98.40
Q4 2023	92,831	$7,388	$66.86	$55.02 - $84.24
Q3 2023	125,581	$8,777	$74.75	$67.52 - $83.30
Q2 2023	275,902	$19,826	$73.77	$56.75 - $91.29
Q1 2023	21,744	$1,341	$65.70	$53.71 - $77.70
Q4 2022	175,899	$13,567	$59.77	$38.87 - $82.00
Q3 2022	182,870	$8,159	$49.97	$35.16 - $71.98
Q2 2022	41,895	$1,604	$31.63	$20.63 - $47.40
Q1 2022	40,559	$1,679	$31.00	$21.85 - $41.95
Q4 2021	398,794	$15,067	$36.79	$29.60 - $44.83
Q3 2021	293,332	$9,668	$38.97	$19.38 - $68.74
Q2 2021	102,711	$6,929	$60.01	$50.05 - $74.10
Q1 2021	92,172	$5,219	$70.34	$55.30 - $82.98
Q4 2020	72,254	$5,887	$74.78	$65.00 - $87.24
Q3 2020	179,255	$12,772	$77.92	$65.25 - $90.00
Q2 2020	60,039	$4,939	$76.97	$49.12 - $109.53
Q1 2020	110,160	$6,481	$81.48	$35.44 - $104.79
Q4 2019	167,656	$17,329	$40.39	$13.64 - $109.94
Q3 2019	12,450	$252	$25.70	$20.10 - $30.50
Q2 2019	12,058	$310	$20.04	$12.76 - $26.45
Q1 2019	19,150	$273	$9.29	$2.52 - $16.80