AXSOME THERAPEUTICS INC

Ticker: AXSM CUSIP: 05464T104 Class: Common Stock

Connor, Clark & Lunn Investment Management Ltd.'s Holding History (CIK: 0001596800)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 188,258 Value ($000) $34,383 Avg Close $139.61 Range $117.30 - $184.40

Q3 2025

Shares 209,069 Value ($000) $25,391 Avg Close $112.64 Range $96.09 - $130.00

Q2 2025

Shares 224,721 Value ($000) $23,459 Avg Close $105.89 Range $86.99 - $120.00

Q1 2025

Shares 175,942 Value ($000) $20,520 Avg Close $113.93 Range $79.19 - $139.13

Q4 2024

Shares 73,497 Value ($000) $6,219 Avg Close $91.96 Range $75.56 - $105.00

Q4 2023

Shares 14,339 Value ($000) $1,141 Avg Close $66.86 Range $55.02 - $84.24

Q1 2022

Shares 9,195 Value ($000) $381 Avg Close $31.00 Range $21.85 - $41.95

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	188,258	$34,383	$139.61	$117.30 - $184.40
Q3 2025	209,069	$25,391	$112.64	$96.09 - $130.00
Q2 2025	224,721	$23,459	$105.89	$86.99 - $120.00
Q1 2025	175,942	$20,520	$113.93	$79.19 - $139.13
Q4 2024	73,497	$6,219	$91.96	$75.56 - $105.00
Q4 2023	14,339	$1,141	$66.86	$55.02 - $84.24
Q1 2022	9,195	$381	$31.00	$21.85 - $41.95