BIOCRYST PHARMACEUTICALS INC

Ticker: BCRX CUSIP: 09058V103 Class: Common Stock

Joel Isaacson & Co., LLC's Holding History (CIK: 0001599330)

Note: Option positions (PUT/CALL) are excluded.

Q4 2016
Shares 9,000 Value ($000) $57 Avg Close $5.20 Range $3.75 - $7.56
Q3 2016
Shares 9,000 Value ($000) $40 Avg Close $3.99 Range $2.82 - $5.80
Q2 2016
Shares 9,000 Value ($000) $26 Avg Close $3.10 Range $2.49 - $4.03
Q1 2016
Shares 9,000 Value ($000) $25 Avg Close $4.43 Range $1.63 - $10.24
Q4 2015
Shares 9,000 Value ($000) $93 Avg Close $9.94 Range $8.01 - $12.88
Q3 2015
Shares 9,000 Value ($000) $103 Avg Close $13.34 Range $10.26 - $16.83
Q2 2015
Shares 12,000 Value ($000) $179 Avg Close $11.37 Range $8.50 - $16.43
Q1 2015
Shares 12,000 Value ($000) $108 Avg Close $10.35 Range $7.85 - $12.71
Q4 2014
Shares 12,000 Value ($000) $146 Avg Close $11.05 Range $9.02 - $13.28
Q3 2014
Shares 12,000 Value ($000) $117 Avg Close $12.26 Range $9.78 - $14.62
Q2 2014
Shares 12,000 Value ($000) $153 Avg Close $9.73 Range $7.29 - $12.86
Q1 2014
Shares 12,000 Value ($000) $127 Avg Close $10.66 Range $7.46 - $13.33
Q4 2013
Shares 12,000 Value ($000) $91 Avg Close $6.33 Range $4.55 - $7.84
Q3 2013
Shares 12,000 Value ($000) $87 Avg Close $5.07 Range $1.51 - $7.59
Q2 2013
Shares 12,000 Value ($000) $19 Avg Close $1.73 Range $1.26 - $2.21
Q1 2013
Shares 12,000 Value ($000) $14 Avg Close $1.45 Range $1.12 - $2.04
Q4 2012
Shares 12,000 Value ($000) $17 Avg Close — Range —