BIOCRYST PHARMACEUTICALS INC

Ticker: BCRX CUSIP: 09058V103 Class: Common Stock

Sofinnova Investments, Inc.'s Holding History (CIK: 0001631134)

Note: Option positions (PUT/CALL) are excluded.

Q4 2021

Shares 1,510,473 Value ($000) $20,920 Avg Close $13.23 Range $10.72 - $15.77

Q2 2021

Shares 158,609 Value ($000) $2,508 Avg Close $13.59 Range $9.23 - $17.74

Q1 2021

Shares 378,774 Value ($000) $3,852 Avg Close $10.31 Range $7.27 - $14.24

Q4 2020

Shares 1,122,800 Value ($000) $8,365 Avg Close $5.16 Range $3.36 - $8.99

Q3 2020

Shares 793,054 Value ($000) $2,725 Avg Close $4.29 Range $3.30 - $6.03

Q2 2020

Shares 1,357,848 Value ($000) $6,470 Avg Close $3.99 Range $1.80 - $6.29

Q1 2020

Shares 815,690 Value ($000) $1,632 Avg Close $2.75 Range $1.58 - $4.35

Q4 2019

Shares 2,151,164 Value ($000) $7,421 Avg Close $2.52 Range $1.38 - $3.48

Q3 2019

Shares 516,734 Value ($000) $1,481 Avg Close $3.11 Range $2.49 - $3.98

Q2 2019

Shares 426,400 Value ($000) $1,616 Avg Close $6.02 Range $2.80 - $9.26

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2021	1,510,473	$20,920	$13.23	$10.72 - $15.77
Q2 2021	158,609	$2,508	$13.59	$9.23 - $17.74
Q1 2021	378,774	$3,852	$10.31	$7.27 - $14.24
Q4 2020	1,122,800	$8,365	$5.16	$3.36 - $8.99
Q3 2020	793,054	$2,725	$4.29	$3.30 - $6.03
Q2 2020	1,357,848	$6,470	$3.99	$1.80 - $6.29
Q1 2020	815,690	$1,632	$2.75	$1.58 - $4.35
Q4 2019	2,151,164	$7,421	$2.52	$1.38 - $3.48
Q3 2019	516,734	$1,481	$3.11	$2.49 - $3.98
Q2 2019	426,400	$1,616	$6.02	$2.80 - $9.26