BIOFRONTERA AG

CUSIP: 09075G105 Class: COM

Opaleye Management Inc.'s Holding History (CIK: 0001595855)

Note: Option positions (PUT/CALL) are excluded.

Q3 2018
Shares 79,007 Value ($000) $1,073 Avg Close — Range —
Q2 2018
Shares 391,400 Value ($000) $4,755 Avg Close — Range —