C4 THERAPEUTICS INC

Ticker: CCCC CUSIP: 12529R107 Class: Common Stock

CLOUGH CAPITAL PARTNERS L P's Holding History (CIK: 0001276144)

Note: Option positions (PUT/CALL) are excluded.

Q1 2022

Shares 356,181 Value ($000) $8,641 Avg Close $24.28 Range $19.81 - $33.76

Q4 2021

Shares 255,681 Value ($000) $8,233 Avg Close $39.55 Range $27.84 - $48.75

Q3 2021

Shares 347,500 Value ($000) $15,526 Avg Close $42.82 Range $34.47 - $51.21

Q2 2021

Shares 125,600 Value ($000) $4,753 Avg Close $35.81 Range $29.55 - $43.50

Period	Shares	Value ($000)	Average Close	Price Range
Q1 2022	356,181	$8,641	$24.28	$19.81 - $33.76
Q4 2021	255,681	$8,233	$39.55	$27.84 - $48.75
Q3 2021	347,500	$15,526	$42.82	$34.47 - $51.21
Q2 2021	125,600	$4,753	$35.81	$29.55 - $43.50