CARA THERAPEUTICS INC

CUSIP: 140755109 Class: Common Stock

SPHERA FUNDS MANAGEMENT LTD.'s Holding History (CIK: 0001496201)

Note: Option positions (PUT/CALL) are excluded.

Q1 2019
Shares 303,930 Value ($000) $5,963 Avg Close — Range —
Q4 2018
Shares 303,930 Value ($000) $3,951 Avg Close — Range —
Q3 2018
Shares 255,930 Value ($000) $6,130 Avg Close — Range —
Q4 2015
Shares 197,820 Value ($000) $3,335 Avg Close — Range —
Q3 2015
Shares 219,800 Value ($000) $3,141 Avg Close — Range —
Q2 2015
Shares 46,700 Value ($000) $567 Avg Close — Range —