CARBYLAN THERAPEUTICS INC

CUSIP: 141384107 Class: COM

SPHERA FUNDS MANAGEMENT LTD.'s Holding History (CIK: 0001496201)

Note: Option positions (PUT/CALL) are excluded.

Q4 2015
Shares 360,000 Value ($000) $1,303 Avg Close — Range —
Q3 2015
Shares 400,000 Value ($000) $1,428 Avg Close — Range —
Q2 2015
Shares 400,000 Value ($000) $2,860 Avg Close — Range —