CARDIOME PHARMA CORP

CUSIP: 14159U301 Class: COM NO PAR

RENAISSANCE TECHNOLOGIES LLC's Holding History (CIK: 0001037389)

Note: Option positions (PUT/CALL) are excluded.

Q1 2018
Shares 528,913 Value ($000) $1,227 Avg Close — Range —
Q4 2017
Shares 486,613 Value ($000) $754 Avg Close — Range —
Q3 2017
Shares 411,413 Value ($000) $876 Avg Close — Range —
Q2 2017
Shares 350,713 Value ($000) $1,585 Avg Close — Range —
Q1 2017
Shares 253,413 Value ($000) $763 Avg Close — Range —
Q4 2016
Shares 215,013 Value ($000) $593 Avg Close — Range —
Q3 2016
Shares 162,613 Value ($000) $509 Avg Close — Range —
Q2 2016
Shares 90,213 Value ($000) $462 Avg Close — Range —
Q1 2016
Shares 65,313 Value ($000) $267 Avg Close — Range —
Q4 2015
Shares 62,213 Value ($000) $505 Avg Close — Range —
Q3 2015
Shares 66,613 Value ($000) $562 Avg Close — Range —
Q2 2015
Shares 91,647 Value ($000) $862 Avg Close — Range —
Q1 2015
Shares 97,113 Value ($000) $899 Avg Close — Range —
Q4 2014
Shares 77,113 Value ($000) $713 Avg Close — Range —
Q3 2014
Shares 84,113 Value ($000) $751 Avg Close — Range —
Q2 2014
Shares 143,298 Value ($000) $1,125 Avg Close — Range —
Q1 2014
Shares 220,613 Value ($000) $1,745 Avg Close — Range —
Q4 2013
Shares 218,913 Value ($000) $1,364 Avg Close — Range —
Q3 2013
Shares 210,113 Value ($000) $744 Avg Close — Range —
Q2 2013
Shares 199,813 Value ($000) $390 Avg Close — Range —