COLLEGIUM PHARMACEUTICAL INC

Ticker: COLL CUSIP: 19459J104 Class: Common Stock

Opaleye Management Inc.'s Holding History (CIK: 0001595855)

Note: Option positions (PUT/CALL) are excluded.

Q4 2018

Shares 80,000 Value ($000) $1,373 Avg Close $17.11 Range $13.70 - $19.83

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2018	80,000	$1,373	$17.11	$13.70 - $19.83