CONTINEUM THERAPEUTICS INC

Ticker: CTNM CUSIP: 21217B100 Class: Common Stock

BAKER BROS. ADVISORS LP's Holding History (CIK: 0001263508)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 1,420,838 Value ($000) $16,240 Avg Close $11.41 Range $10.07 - $13.48

Q3 2025

Shares 77,670 Value ($000) $913 Avg Close $8.06 Range $3.72 - $13.49

Q2 2025

Shares 312,500 Value ($000) $1,241 Avg Close $4.35 Range $3.35 - $6.97

Q1 2025

Shares 312,500 Value ($000) $2,181 Avg Close $9.10 Range $5.92 - $15.25

Q4 2024

Shares 312,500 Value ($000) $4,578 Avg Close $15.84 Range $12.33 - $20.24

Q3 2024

Shares 312,500 Value ($000) $5,981 Avg Close $19.17 Range $15.95 - $22.00

Q2 2024

Shares 312,500 Value ($000) $5,503 Avg Close $16.10 Range $13.27 - $21.35

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	1,420,838	$16,240	$11.41	$10.07 - $13.48
Q3 2025	77,670	$913	$8.06	$3.72 - $13.49
Q2 2025	312,500	$1,241	$4.35	$3.35 - $6.97
Q1 2025	312,500	$2,181	$9.10	$5.92 - $15.25
Q4 2024	312,500	$4,578	$15.84	$12.33 - $20.24
Q3 2024	312,500	$5,981	$19.17	$15.95 - $22.00
Q2 2024	312,500	$5,503	$16.10	$13.27 - $21.35