CONTINEUM THERAPEUTICS INC

Ticker: CTNM CUSIP: 21217B100 Class: Common Stock

TWO SIGMA ADVISERS, LP's Holding History (CIK: 0001478735)

Note: Option positions (PUT/CALL) are excluded.

Q2 2025

Shares 43,200 Value ($000) $172 Avg Close $4.35 Range $3.35 - $6.97

Period	Shares	Value ($000)	Average Close	Price Range
Q2 2025	43,200	$172	$4.35	$3.35 - $6.97