CRINETICS PHARMACEUTICALS IN

Ticker: CRNX CUSIP: 22663K107 Class: EQTY

STATE OF WISCONSIN INVESTMENT BOARD's Holding History (CIK: 0000854157)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 55,561 Value ($000) $2,586 Avg Close $44.52 Range $38.81 - $50.98

Q3 2025

Shares 57,025 Value ($000) $2,375 Avg Close $31.97 Range $25.83 - $47.41

Q2 2025

Shares 64,587 Value ($000) $1,858 Avg Close $30.88 Range $24.10 - $34.68

Q1 2025

Shares 63,555 Value ($000) $2,132 Avg Close $37.35 Range $31.65 - $53.55

Q4 2024

Shares 75,103 Value ($000) $3,840 Avg Close $55.95 Range $49.48 - $62.53

Q3 2024

Shares 65,394 Value ($000) $3,342 Avg Close $51.57 Range $43.71 - $55.78

Q2 2024

Shares 60,416 Value ($000) $2,706 Avg Close $46.18 Range $41.01 - $53.70

Q1 2024

Shares 50,111 Value ($000) $2,346 Avg Close $39.13 Range $33.67 - $47.58

Q4 2023

Shares 57,768 Value ($000) $2,055 Avg Close $30.67 Range $25.35 - $37.88

Q3 2023

Shares 50,272 Value ($000) $1,495 Avg Close $20.61 Range $15.76 - $31.00

Q2 2023

Shares 39,398 Value ($000) $710 Avg Close $19.94 Range $15.50 - $24.58

Q1 2023

Shares 34,767 Value ($000) $558 Avg Close $18.51 Range $15.23 - $21.65

Q4 2022

Shares 35,794 Value ($000) $655 Avg Close $17.62 Range $15.37 - $19.97

Q3 2022

Shares 38,097 Value ($000) $748 Avg Close $20.39 Range $17.79 - $22.85

Q2 2022

Shares 36,570 Value ($000) $682 Avg Close $19.96 Range $15.91 - $27.86

Q1 2022

Shares 61,300 Value ($000) $1,346 Avg Close $20.24 Range $16.53 - $28.95

Q4 2021

Shares 68,200 Value ($000) $1,938 Avg Close $24.65 Range $18.97 - $28.82

Q3 2021

Shares 38,600 Value ($000) $813 Avg Close $20.92 Range $16.68 - $25.50

Q2 2021

Shares 38,600 Value ($000) $728 Avg Close $17.57 Range $15.15 - $21.64

Q1 2021

Shares 38,600 Value ($000) $590 Avg Close $15.50 Range $13.29 - $18.09

Q4 2020

Shares 38,600 Value ($000) $545 Avg Close $13.93 Range $11.61 - $17.84

Q3 2020

Shares 43,400 Value ($000) $680 Avg Close $15.29 Range $13.12 - $18.12

Q2 2020

Shares 17,100 Value ($000) $300 Avg Close $17.05 Range $12.50 - $23.70

Q1 2020

Shares 17,100 Value ($000) $251 Avg Close $20.50 Range $10.63 - $26.67

Q4 2019

Shares 16,600 Value ($000) $416 Avg Close $19.04 Range $14.91 - $25.41

Q3 2019

Shares 16,600 Value ($000) $250 Avg Close $19.45 Range $14.33 - $26.27

Q2 2019

Shares 9,700 Value ($000) $242 Avg Close $24.76 Range $21.27 - $28.80

Q1 2019

Shares 9,500 Value ($000) $216 Avg Close $24.58 Range $21.05 - $30.61

Q4 2018

Shares 7,400 Value ($000) $222 Avg Close $28.15 Range $20.13 - $36.95

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	55,561	$2,586	$44.52	$38.81 - $50.98
Q3 2025	57,025	$2,375	$31.97	$25.83 - $47.41
Q2 2025	64,587	$1,858	$30.88	$24.10 - $34.68
Q1 2025	63,555	$2,132	$37.35	$31.65 - $53.55
Q4 2024	75,103	$3,840	$55.95	$49.48 - $62.53
Q3 2024	65,394	$3,342	$51.57	$43.71 - $55.78
Q2 2024	60,416	$2,706	$46.18	$41.01 - $53.70
Q1 2024	50,111	$2,346	$39.13	$33.67 - $47.58
Q4 2023	57,768	$2,055	$30.67	$25.35 - $37.88
Q3 2023	50,272	$1,495	$20.61	$15.76 - $31.00
Q2 2023	39,398	$710	$19.94	$15.50 - $24.58
Q1 2023	34,767	$558	$18.51	$15.23 - $21.65
Q4 2022	35,794	$655	$17.62	$15.37 - $19.97
Q3 2022	38,097	$748	$20.39	$17.79 - $22.85
Q2 2022	36,570	$682	$19.96	$15.91 - $27.86
Q1 2022	61,300	$1,346	$20.24	$16.53 - $28.95
Q4 2021	68,200	$1,938	$24.65	$18.97 - $28.82
Q3 2021	38,600	$813	$20.92	$16.68 - $25.50
Q2 2021	38,600	$728	$17.57	$15.15 - $21.64
Q1 2021	38,600	$590	$15.50	$13.29 - $18.09
Q4 2020	38,600	$545	$13.93	$11.61 - $17.84
Q3 2020	43,400	$680	$15.29	$13.12 - $18.12
Q2 2020	17,100	$300	$17.05	$12.50 - $23.70
Q1 2020	17,100	$251	$20.50	$10.63 - $26.67
Q4 2019	16,600	$416	$19.04	$14.91 - $25.41
Q3 2019	16,600	$250	$19.45	$14.33 - $26.27
Q2 2019	9,700	$242	$24.76	$21.27 - $28.80
Q1 2019	9,500	$216	$24.58	$21.05 - $30.61
Q4 2018	7,400	$222	$28.15	$20.13 - $36.95