CYTOKINETICS INC

Ticker: CYTK CUSIP: 23282W605 Class: EQTY

CULLEN/FROST BANKERS, INC.'s Holding History (CIK: 0000039263)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 352 Value ($000) $22 Avg Close $62.21 Range $53.61 - $70.98

Q3 2025

Shares 263 Value ($000) $14 Avg Close $41.20 Range $32.66 - $55.92

Q2 2025

Shares 203 Value ($000) $7 Avg Close $34.78 Range $29.31 - $43.69

Q1 2025

Shares 142 Value ($000) $6 Avg Close $45.96 Range $39.81 - $52.80

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	352	$22	$62.21	$53.61 - $70.98
Q3 2025	263	$14	$41.20	$32.66 - $55.92
Q2 2025	203	$7	$34.78	$29.31 - $43.69
Q1 2025	142	$6	$45.96	$39.81 - $52.80