CYTOKINETICS INC

Ticker: CYTK CUSIP: 23282W605 Class: EQTY

ADAGE CAPITAL PARTNERS GP, L.L.C.'s Holding History (CIK: 0001165408)

Note: Option positions (PUT/CALL) are excluded.

Q3 2025

Shares 38,000 Value ($000) $2,088 Avg Close $41.20 Range $32.66 - $55.92

Q1 2024

Shares 37,500 Value ($000) $2,629 Avg Close $77.34 Range $61.33 - $110.25

Q4 2023

Shares 30,000 Value ($000) $2,505 Avg Close $36.21 Range $25.98 - $87.58

Q2 2021

Shares 711,407 Value ($000) $14,079 Avg Close $23.48 Range $19.52 - $28.12

Q1 2021

Shares 1,550,000 Value ($000) $36,053 Avg Close $21.35 Range $18.00 - $25.82

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2025	38,000	$2,088	$41.20	$32.66 - $55.92
Q1 2024	37,500	$2,629	$77.34	$61.33 - $110.25
Q4 2023	30,000	$2,505	$36.21	$25.98 - $87.58
Q2 2021	711,407	$14,079	$23.48	$19.52 - $28.12
Q1 2021	1,550,000	$36,053	$21.35	$18.00 - $25.82