CYTOMX THERAPEUTICS INC

Ticker: CTMX CUSIP: 23284F105 Class: COM

TWO SIGMA ADVISERS, LP's Holding History (CIK: 0001478735)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 335,524 Value ($000) $1,429 Avg Close $3.80 Range $3.06 - $4.62

Q3 2025

Shares 40,000 Value ($000) $128 Avg Close $2.25 Range $1.72 - $3.28

Q2 2024

Shares 158,400 Value ($000) $193 Avg Close $1.99 Range $1.13 - $5.85

Q1 2024

Shares 146,800 Value ($000) $320 Avg Close $1.85 Range $1.38 - $2.85

Q4 2023

Shares 41,200 Value ($000) $64 Avg Close $1.31 Range $1.04 - $1.60

Q3 2023

Shares 107,900 Value ($000) $139 Avg Close $1.57 Range $1.22 - $1.89

Q2 2023

Shares 229,400 Value ($000) $395 Avg Close $1.66 Range $1.40 - $1.95

Q1 2023

Shares 516,100 Value ($000) $779 Avg Close $2.26 Range $1.43 - $3.02

Q4 2022

Shares 524,900 Value ($000) $840 Avg Close $1.48 Range $1.17 - $1.94

Q3 2022

Shares 527,400 Value ($000) $765 Avg Close $1.54 Range $1.19 - $2.01

Q2 2022

Shares 387,000 Value ($000) $708 Avg Close $1.91 Range $1.50 - $3.02

Q1 2022

Shares 348,300 Value ($000) $930 Avg Close $3.84 Range $2.57 - $4.73

Q4 2021

Shares 201,600 Value ($000) $873 Avg Close $5.86 Range $3.68 - $7.53

Q3 2021

Shares 201,200 Value ($000) $1,024 Avg Close $5.35 Range $4.28 - $6.47

Q2 2021

Shares 369,100 Value ($000) $2,336 Avg Close $7.79 Range $6.33 - $10.05

Q1 2021

Shares 650,900 Value ($000) $5,031 Avg Close $7.92 Range $6.43 - $9.42

Q4 2020

Shares 692,900 Value ($000) $4,538 Avg Close $7.14 Range $6.40 - $8.00

Q3 2020

Shares 554,100 Value ($000) $3,685 Avg Close $7.42 Range $6.25 - $9.29

Q2 2020

Shares 541,800 Value ($000) $4,513 Avg Close $9.29 Range $7.01 - $15.44

Q1 2020

Shares 487,700 Value ($000) $3,741 Avg Close $6.97 Range $3.60 - $8.63

Q4 2019

Shares 480,100 Value ($000) $3,990 Avg Close $6.75 Range $5.10 - $9.00

Q3 2019

Shares 234,900 Value ($000) $1,734 Avg Close $9.86 Range $7.34 - $12.63

Q2 2019

Shares 253,200 Value ($000) $2,841 Avg Close $10.48 Range $8.94 - $11.69

Q1 2019

Shares 251,100 Value ($000) $2,699 Avg Close $14.78 Range $9.38 - $19.75

Q4 2018

Shares 254,100 Value ($000) $3,837 Avg Close $14.84 Range $12.51 - $18.66

Q3 2018

Shares 264,900 Value ($000) $4,901 Avg Close $22.78 Range $17.61 - $27.20

Q2 2018

Shares 274,100 Value ($000) $6,266 Avg Close $25.54 Range $19.86 - $30.73

Q1 2018

Shares 188,800 Value ($000) $5,371 Avg Close $28.54 Range $20.52 - $35.00

Q4 2017

Shares 122,100 Value ($000) $2,578 Avg Close $20.73 Range $18.10 - $24.67

Q3 2017

Shares 52,900 Value ($000) $961 Avg Close $15.60 Range $13.09 - $18.31

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	335,524	$1,429	$3.80	$3.06 - $4.62
Q3 2025	40,000	$128	$2.25	$1.72 - $3.28
Q2 2024	158,400	$193	$1.99	$1.13 - $5.85
Q1 2024	146,800	$320	$1.85	$1.38 - $2.85
Q4 2023	41,200	$64	$1.31	$1.04 - $1.60
Q3 2023	107,900	$139	$1.57	$1.22 - $1.89
Q2 2023	229,400	$395	$1.66	$1.40 - $1.95
Q1 2023	516,100	$779	$2.26	$1.43 - $3.02
Q4 2022	524,900	$840	$1.48	$1.17 - $1.94
Q3 2022	527,400	$765	$1.54	$1.19 - $2.01
Q2 2022	387,000	$708	$1.91	$1.50 - $3.02
Q1 2022	348,300	$930	$3.84	$2.57 - $4.73
Q4 2021	201,600	$873	$5.86	$3.68 - $7.53
Q3 2021	201,200	$1,024	$5.35	$4.28 - $6.47
Q2 2021	369,100	$2,336	$7.79	$6.33 - $10.05
Q1 2021	650,900	$5,031	$7.92	$6.43 - $9.42
Q4 2020	692,900	$4,538	$7.14	$6.40 - $8.00
Q3 2020	554,100	$3,685	$7.42	$6.25 - $9.29
Q2 2020	541,800	$4,513	$9.29	$7.01 - $15.44
Q1 2020	487,700	$3,741	$6.97	$3.60 - $8.63
Q4 2019	480,100	$3,990	$6.75	$5.10 - $9.00
Q3 2019	234,900	$1,734	$9.86	$7.34 - $12.63
Q2 2019	253,200	$2,841	$10.48	$8.94 - $11.69
Q1 2019	251,100	$2,699	$14.78	$9.38 - $19.75
Q4 2018	254,100	$3,837	$14.84	$12.51 - $18.66
Q3 2018	264,900	$4,901	$22.78	$17.61 - $27.20
Q2 2018	274,100	$6,266	$25.54	$19.86 - $30.73
Q1 2018	188,800	$5,371	$28.54	$20.52 - $35.00
Q4 2017	122,100	$2,578	$20.73	$18.10 - $24.67
Q3 2017	52,900	$961	$15.60	$13.09 - $18.31