DAY ONE BIOPHARMACEUTICALS I

Ticker: DAWN CUSIP: 23954D109 Class: Common Stock

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q1 2025

Shares 69,895 Value ($000) $554 Avg Close $10.77 Range $7.54 - $13.53

Q4 2024

Shares 271,776 Value ($000) $3,443 Avg Close $13.91 Range $12.11 - $16.76

Q3 2024

Shares 407,501 Value ($000) $5,676 Avg Close $14.27 Range $12.53 - $16.75

Q2 2024

Shares 299,206 Value ($000) $4,123 Avg Close $14.63 Range $11.94 - $18.07

Q1 2024

Shares 20,412 Value ($000) $337 Avg Close $14.97 Range $13.42 - $17.85

Q1 2023

Shares 153,569 Value ($000) $2,053 Avg Close $19.53 Range $11.98 - $25.77

Q1 2022

Shares 60,190 Value ($000) $597 Avg Close $13.21 Range $9.03 - $17.70

Period	Shares	Value ($000)	Average Close	Price Range
Q1 2025	69,895	$554	$10.77	$7.54 - $13.53
Q4 2024	271,776	$3,443	$13.91	$12.11 - $16.76
Q3 2024	407,501	$5,676	$14.27	$12.53 - $16.75
Q2 2024	299,206	$4,123	$14.63	$11.94 - $18.07
Q1 2024	20,412	$337	$14.97	$13.42 - $17.85
Q1 2023	153,569	$2,053	$19.53	$11.98 - $25.77
Q1 2022	60,190	$597	$13.21	$9.03 - $17.70