DAY ONE BIOPHARMACEUTICALS I

Ticker: DAWN CUSIP: 23954D109 Class: Common Stock

Brevan Howard Capital Management LP's Holding History (CIK: 0001512857)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 43,284 Value ($000) $403 Avg Close $8.35 Range $6.70 - $10.90

Q3 2025

Shares 24,208 Value ($000) $171 Avg Close $6.88 Range $5.63 - $7.74

Q3 2024

Shares 11,979 Value ($000) $167 Avg Close $14.27 Range $12.53 - $16.75

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	43,284	$403	$8.35	$6.70 - $10.90
Q3 2025	24,208	$171	$6.88	$5.63 - $7.74
Q3 2024	11,979	$167	$14.27	$12.53 - $16.75