DENALI THERAPEUTICS INC

Ticker: DNLI CUSIP: 24823R105 Class: Common Stock

ESSEX INVESTMENT MANAGEMENT CO LLC's Holding History (CIK: 0000201772)

Note: Option positions (PUT/CALL) are excluded.

Q1 2019

Shares 8,130 Value ($000) $189 Avg Close $20.92 Range $17.73 - $25.05

Q4 2018

Shares 8,820 Value ($000) $182 Avg Close $18.14 Range $13.78 - $22.40

Period	Shares	Value ($000)	Average Close	Price Range
Q1 2019	8,130	$189	$20.92	$17.73 - $25.05
Q4 2018	8,820	$182	$18.14	$13.78 - $22.40