DENALI THERAPEUTICS INC

Ticker: DNLI CUSIP: 24823R105 Class: Common Stock

FIRST MANHATTAN CO. LLC.'s Holding History (CIK: 0000728083)

Note: Option positions (PUT/CALL) are excluded.

Q2 2021

Shares 200 Value ($000) $15 Avg Close $61.86 Range $49.20 - $79.70

Q1 2021

Shares 200 Value ($000) $11 Avg Close $66.94 Range $52.23 - $84.25

Q4 2020

Shares 200 Value ($000) $16 Avg Close $60.45 Range $35.89 - $93.94

Q3 2020

Shares 200 Value ($000) $7 Avg Close $30.12 Range $22.36 - $39.22

Period	Shares	Value ($000)	Average Close	Price Range
Q2 2021	200	$15	$61.86	$49.20 - $79.70
Q1 2021	200	$11	$66.94	$52.23 - $84.25
Q4 2020	200	$16	$60.45	$35.89 - $93.94
Q3 2020	200	$7	$30.12	$22.36 - $39.22