DENALI THERAPEUTICS INC

Ticker: DNLI CUSIP: 24823R105 Class: Common Stock

NISA INVESTMENT ADVISORS, LLC's Holding History (CIK: 0000937615)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 1,449 Value ($000) $24 Avg Close $16.88 Range $13.75 - $20.61

Q3 2025

Shares 1,483 Value ($000) $22 Avg Close $14.37 Range $12.58 - $16.20

Q2 2025

Shares 1,217 Value ($000) $17 Avg Close $14.07 Range $10.57 - $16.97

Q1 2025

Shares 1,416 Value ($000) $19 Avg Close $19.16 Range $13.30 - $24.34

Q4 2024

Shares 66,621 Value ($000) $1,358 Avg Close $25.60 Range $19.93 - $33.33

Q3 2024

Shares 66,482 Value ($000) $1,937 Avg Close $24.79 Range $19.74 - $32.13

Q2 2024

Shares 66,322 Value ($000) $1,540 Avg Close $19.20 Range $14.56 - $23.87

Q1 2024

Shares 66,129 Value ($000) $1,357 Avg Close $18.79 Range $15.49 - $23.52

Q4 2023

Shares 66,059 Value ($000) $1,418 Avg Close $19.81 Range $15.45 - $23.81

Q3 2023

Shares 17,960 Value ($000) $371 Avg Close $25.37 Range $20.52 - $30.79

Q2 2023

Shares 17,950 Value ($000) $530 Avg Close $28.12 Range $22.72 - $33.31

Q1 2023

Shares 17,758 Value ($000) $0 Avg Close $27.52 Range $21.74 - $32.81

Q4 2022

Shares 17,918 Value ($000) $0 Avg Close $29.75 Range $25.96 - $34.78

Q3 2022

Shares 17,918 Value ($000) $544 Avg Close $32.51 Range $25.88 - $39.43

Q2 2022

Shares 17,816 Value ($000) $524 Avg Close $26.20 Range $20.24 - $35.62

Q1 2022

Shares 2,616 Value ($000) $84 Avg Close $34.41 Range $28.76 - $47.47

Q4 2021

Shares 3,851 Value ($000) $132 Avg Close $47.38 Range $41.10 - $56.08

Q3 2021

Shares 6,146 Value ($000) $310 Avg Close $56.36 Range $47.02 - $79.50

Q2 2021

Shares 6,194 Value ($000) $486 Avg Close $61.86 Range $49.20 - $79.70

Q1 2021

Shares 6,294 Value ($000) $359 Avg Close $66.94 Range $52.23 - $84.25

Q4 2020

Shares 5,844 Value ($000) $489 Avg Close $60.45 Range $35.89 - $93.94

Q3 2020

Shares 2,590 Value ($000) $93 Avg Close $30.12 Range $22.36 - $39.22

Q2 2020

Shares 760 Value ($000) $18 Avg Close $23.51 Range $15.72 - $29.39

Q1 2020

Shares 460 Value ($000) $8 Avg Close $20.86 Range $12.39 - $30.41

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	1,449	$24	$16.88	$13.75 - $20.61
Q3 2025	1,483	$22	$14.37	$12.58 - $16.20
Q2 2025	1,217	$17	$14.07	$10.57 - $16.97
Q1 2025	1,416	$19	$19.16	$13.30 - $24.34
Q4 2024	66,621	$1,358	$25.60	$19.93 - $33.33
Q3 2024	66,482	$1,937	$24.79	$19.74 - $32.13
Q2 2024	66,322	$1,540	$19.20	$14.56 - $23.87
Q1 2024	66,129	$1,357	$18.79	$15.49 - $23.52
Q4 2023	66,059	$1,418	$19.81	$15.45 - $23.81
Q3 2023	17,960	$371	$25.37	$20.52 - $30.79
Q2 2023	17,950	$530	$28.12	$22.72 - $33.31
Q1 2023	17,758	$0	$27.52	$21.74 - $32.81
Q4 2022	17,918	$0	$29.75	$25.96 - $34.78
Q3 2022	17,918	$544	$32.51	$25.88 - $39.43
Q2 2022	17,816	$524	$26.20	$20.24 - $35.62
Q1 2022	2,616	$84	$34.41	$28.76 - $47.47
Q4 2021	3,851	$132	$47.38	$41.10 - $56.08
Q3 2021	6,146	$310	$56.36	$47.02 - $79.50
Q2 2021	6,194	$486	$61.86	$49.20 - $79.70
Q1 2021	6,294	$359	$66.94	$52.23 - $84.25
Q4 2020	5,844	$489	$60.45	$35.89 - $93.94
Q3 2020	2,590	$93	$30.12	$22.36 - $39.22
Q2 2020	760	$18	$23.51	$15.72 - $29.39
Q1 2020	460	$8	$20.86	$12.39 - $30.41