DENALI THERAPEUTICS INC

Ticker: DNLI CUSIP: 24823R105 Class: Common Stock

SCHRODER INVESTMENT MANAGEMENT GROUP's Holding History (CIK: 0001086619)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 450,985 Value ($000) $7,401 Avg Close $16.88 Range $13.75 - $20.61

Q3 2025

Shares 209,595 Value ($000) $3,043 Avg Close $14.37 Range $12.58 - $16.20

Q2 2025

Shares 386,539 Value ($000) $5,408 Avg Close $14.07 Range $10.57 - $16.97

Q1 2025

Shares 291,795 Value ($000) $4,313 Avg Close $19.16 Range $13.30 - $24.34

Q4 2024

Shares 247,800 Value ($000) $5,015 Avg Close $25.60 Range $19.93 - $33.33

Q3 2024

Shares 127,306 Value ($000) $3,747 Avg Close $24.79 Range $19.74 - $32.13

Q2 2024

Shares 345,373 Value ($000) $8,020 Avg Close $19.20 Range $14.56 - $23.87

Q4 2023

Shares 154,000 Value ($000) $3,305 Avg Close $19.81 Range $15.45 - $23.81

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	450,985	$7,401	$16.88	$13.75 - $20.61
Q3 2025	209,595	$3,043	$14.37	$12.58 - $16.20
Q2 2025	386,539	$5,408	$14.07	$10.57 - $16.97
Q1 2025	291,795	$4,313	$19.16	$13.30 - $24.34
Q4 2024	247,800	$5,015	$25.60	$19.93 - $33.33
Q3 2024	127,306	$3,747	$24.79	$19.74 - $32.13
Q2 2024	345,373	$8,020	$19.20	$14.56 - $23.87
Q4 2023	154,000	$3,305	$19.81	$15.45 - $23.81