DENALI THERAPEUTICS INC

Ticker: DNLI CUSIP: 24823R105 Class: Common Stock

BAKER BROS. ADVISORS LP's Holding History (CIK: 0001263508)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025
Shares 3,731,695 Value ($000) $61,610 Avg Close $16.88 Range $13.75 - $20.61
Q3 2025
Shares 3,731,695 Value ($000) $54,184 Avg Close $14.37 Range $12.58 - $16.20
Q2 2025
Shares 3,731,695 Value ($000) $52,206 Avg Close $14.07 Range $10.57 - $16.97
Q1 2025
Shares 3,731,695 Value ($000) $50,732 Avg Close $19.16 Range $13.30 - $24.34
Q4 2024
Shares 3,731,695 Value ($000) $76,052 Avg Close $25.60 Range $19.93 - $33.33
Q3 2024
Shares 3,731,695 Value ($000) $108,704 Avg Close $24.79 Range $19.74 - $32.13
Q2 2024
Shares 3,731,695 Value ($000) $86,650 Avg Close $19.20 Range $14.56 - $23.87
Q1 2024
Shares 3,731,695 Value ($000) $76,574 Avg Close $18.79 Range $15.49 - $23.52
Q4 2023
Shares 2,607,196 Value ($000) $55,950 Avg Close $19.81 Range $15.45 - $23.81
Q3 2023
Shares 2,292,003 Value ($000) $47,284 Avg Close $25.37 Range $20.52 - $30.79
Q2 2023
Shares 1,455,322 Value ($000) $42,947 Avg Close $28.12 Range $22.72 - $33.31
Q1 2023
Shares 1,088,738 Value ($000) $25,085 Avg Close $27.52 Range $21.74 - $32.81
Q4 2022
Shares 1,088,738 Value ($000) $30,278 Avg Close $29.75 Range $25.96 - $34.78
Q3 2022
Shares 588,738 Value ($000) $18,068 Avg Close $32.51 Range $25.88 - $39.43
Q2 2022
Shares 588,738 Value ($000) $17,327 Avg Close $26.20 Range $20.24 - $35.62
Q1 2022
Shares 88,738 Value ($000) $2,855 Avg Close $34.41 Range $28.76 - $47.47
Q4 2021
Shares 88,738 Value ($000) $3,958 Avg Close $47.38 Range $41.10 - $56.08
Q3 2021
Shares 88,738 Value ($000) $4,477 Avg Close $56.36 Range $47.02 - $79.50
Q2 2021
Shares 88,738 Value ($000) $6,961 Avg Close $61.86 Range $49.20 - $79.70
Q1 2021
Shares 88,738 Value ($000) $5,067 Avg Close $66.94 Range $52.23 - $84.25
Q4 2020
Shares 88,738 Value ($000) $7,433 Avg Close $60.45 Range $35.89 - $93.94
Q3 2020
Shares 99,400 Value ($000) $3,562 Avg Close $30.12 Range $22.36 - $39.22
Q2 2020
Shares 104,900 Value ($000) $2,536 Avg Close $23.51 Range $15.72 - $29.39
Q1 2020
Shares 104,900 Value ($000) $1,837 Avg Close $20.86 Range $12.39 - $30.41