DENALI THERAPEUTICS INC

Ticker: DNLI CUSIP: 24823R105 Class: Common Stock

CITADEL ADVISORS LLC's Holding History (CIK: 0001423053)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 779,148 Value ($000) $12,864 Avg Close $16.88 Range $13.75 - $20.61

Q3 2025

Shares 688,224 Value ($000) $9,993 Avg Close $14.37 Range $12.58 - $16.20

Q2 2025

Shares 1,248,953 Value ($000) $17,473 Avg Close $14.07 Range $10.57 - $16.97

Q1 2025

Shares 1,169,683 Value ($000) $15,902 Avg Close $19.16 Range $13.30 - $24.34

Q4 2024

Shares 829,911 Value ($000) $16,914 Avg Close $25.60 Range $19.93 - $33.33

Q3 2024

Shares 777,280 Value ($000) $22,642 Avg Close $24.79 Range $19.74 - $32.13

Q2 2024

Shares 1,218,698 Value ($000) $28,298 Avg Close $19.20 Range $14.56 - $23.87

Q1 2024

Shares 1,365,028 Value ($000) $28,010 Avg Close $18.79 Range $15.49 - $23.52

Q4 2023

Shares 68,110 Value ($000) $1,462 Avg Close $19.81 Range $15.45 - $23.81

Q3 2023

Shares 61,905 Value ($000) $1,277 Avg Close $25.37 Range $20.52 - $30.79

Q2 2023

Shares 56,103 Value ($000) $1,656 Avg Close $28.12 Range $22.72 - $33.31

Q1 2023

Shares 1,374,325 Value ($000) $31,664 Avg Close $27.52 Range $21.74 - $32.81

Q4 2022

Shares 34,613 Value ($000) $963 Avg Close $29.75 Range $25.96 - $34.78

Q3 2022

Shares 63,537 Value ($000) $1,950 Avg Close $32.51 Range $25.88 - $39.43

Q2 2022

Shares 306,002 Value ($000) $9,006 Avg Close $26.20 Range $20.24 - $35.62

Q1 2022

Shares 751,603 Value ($000) $24,179 Avg Close $34.41 Range $28.76 - $47.47

Q4 2021

Shares 485,683 Value ($000) $21,662 Avg Close $47.38 Range $41.10 - $56.08

Q3 2021

Shares 63,011 Value ($000) $3,179 Avg Close $56.36 Range $47.02 - $79.50

Q1 2021

Shares 240,784 Value ($000) $13,749 Avg Close $66.94 Range $52.23 - $84.25

Q4 2020

Shares 5,113 Value ($000) $428 Avg Close $60.45 Range $35.89 - $93.94

Q3 2020

Shares 218,137 Value ($000) $7,816 Avg Close $30.12 Range $22.36 - $39.22

Q2 2020

Shares 110,565 Value ($000) $2,673 Avg Close $23.51 Range $15.72 - $29.39

Q1 2020

Shares 72,352 Value ($000) $1,267 Avg Close $20.86 Range $12.39 - $30.41

Q4 2019

Shares 53,586 Value ($000) $933 Avg Close $16.65 Range $14.24 - $20.17

Q3 2019

Shares 88,409 Value ($000) $1,354 Avg Close $19.11 Range $15.29 - $22.26

Q2 2019

Shares 194,876 Value ($000) $4,045 Avg Close $22.41 Range $18.28 - $28.86

Q1 2019

Shares 27,765 Value ($000) $645 Avg Close $20.92 Range $17.73 - $25.05

Q2 2018

Shares 49,421 Value ($000) $753 Avg Close $18.84 Range $15.19 - $22.99

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	779,148	$12,864	$16.88	$13.75 - $20.61
Q3 2025	688,224	$9,993	$14.37	$12.58 - $16.20
Q2 2025	1,248,953	$17,473	$14.07	$10.57 - $16.97
Q1 2025	1,169,683	$15,902	$19.16	$13.30 - $24.34
Q4 2024	829,911	$16,914	$25.60	$19.93 - $33.33
Q3 2024	777,280	$22,642	$24.79	$19.74 - $32.13
Q2 2024	1,218,698	$28,298	$19.20	$14.56 - $23.87
Q1 2024	1,365,028	$28,010	$18.79	$15.49 - $23.52
Q4 2023	68,110	$1,462	$19.81	$15.45 - $23.81
Q3 2023	61,905	$1,277	$25.37	$20.52 - $30.79
Q2 2023	56,103	$1,656	$28.12	$22.72 - $33.31
Q1 2023	1,374,325	$31,664	$27.52	$21.74 - $32.81
Q4 2022	34,613	$963	$29.75	$25.96 - $34.78
Q3 2022	63,537	$1,950	$32.51	$25.88 - $39.43
Q2 2022	306,002	$9,006	$26.20	$20.24 - $35.62
Q1 2022	751,603	$24,179	$34.41	$28.76 - $47.47
Q4 2021	485,683	$21,662	$47.38	$41.10 - $56.08
Q3 2021	63,011	$3,179	$56.36	$47.02 - $79.50
Q1 2021	240,784	$13,749	$66.94	$52.23 - $84.25
Q4 2020	5,113	$428	$60.45	$35.89 - $93.94
Q3 2020	218,137	$7,816	$30.12	$22.36 - $39.22
Q2 2020	110,565	$2,673	$23.51	$15.72 - $29.39
Q1 2020	72,352	$1,267	$20.86	$12.39 - $30.41
Q4 2019	53,586	$933	$16.65	$14.24 - $20.17
Q3 2019	88,409	$1,354	$19.11	$15.29 - $22.26
Q2 2019	194,876	$4,045	$22.41	$18.28 - $28.86
Q1 2019	27,765	$645	$20.92	$17.73 - $25.05
Q2 2018	49,421	$753	$18.84	$15.19 - $22.99