DENALI THERAPEUTICS INC

Ticker: DNLI CUSIP: 24823R105 Class: Common Stock

Holocene Advisors, LP's Holding History (CIK: 0001700574)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 3,152,734 Value ($000) $52,052 Avg Close $16.88 Range $13.75 - $20.61

Q3 2025

Shares 3,135,712 Value ($000) $45,531 Avg Close $14.37 Range $12.58 - $16.20

Q2 2025

Shares 403,172 Value ($000) $5,640 Avg Close $14.07 Range $10.57 - $16.97

Q4 2024

Shares 199,072 Value ($000) $4,057 Avg Close $25.60 Range $19.93 - $33.33

Q3 2024

Shares 97,447 Value ($000) $2,839 Avg Close $24.79 Range $19.74 - $32.13

Q2 2024

Shares 59,042 Value ($000) $1,371 Avg Close $19.20 Range $14.56 - $23.87

Q1 2024

Shares 860,948 Value ($000) $17,667 Avg Close $18.79 Range $15.49 - $23.52

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	3,152,734	$52,052	$16.88	$13.75 - $20.61
Q3 2025	3,135,712	$45,531	$14.37	$12.58 - $16.20
Q2 2025	403,172	$5,640	$14.07	$10.57 - $16.97
Q4 2024	199,072	$4,057	$25.60	$19.93 - $33.33
Q3 2024	97,447	$2,839	$24.79	$19.74 - $32.13
Q2 2024	59,042	$1,371	$19.20	$14.56 - $23.87
Q1 2024	860,948	$17,667	$18.79	$15.49 - $23.52