DENALI THERAPEUTICS INC

Ticker: DNLI CUSIP: 24823R105 Class: Common Stock

Qube Research & Technologies Ltd's Holding History (CIK: 0001729829)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 590,314 Value ($000) $9,746 Avg Close $16.88 Range $13.75 - $20.61

Q3 2025

Shares 227,990 Value ($000) $3,310 Avg Close $14.37 Range $12.58 - $16.20

Q1 2025

Shares 288,221 Value ($000) $3,918 Avg Close $19.16 Range $13.30 - $24.34

Q4 2024

Shares 311,507 Value ($000) $6,349 Avg Close $25.60 Range $19.93 - $33.33

Q1 2024

Shares 37,749 Value ($000) $775 Avg Close $18.79 Range $15.49 - $23.52

Q4 2023

Shares 171,262 Value ($000) $3,675 Avg Close $19.81 Range $15.45 - $23.81

Q3 2023

Shares 13,553 Value ($000) $280 Avg Close $25.37 Range $20.52 - $30.79

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	590,314	$9,746	$16.88	$13.75 - $20.61
Q3 2025	227,990	$3,310	$14.37	$12.58 - $16.20
Q1 2025	288,221	$3,918	$19.16	$13.30 - $24.34
Q4 2024	311,507	$6,349	$25.60	$19.93 - $33.33
Q1 2024	37,749	$775	$18.79	$15.49 - $23.52
Q4 2023	171,262	$3,675	$19.81	$15.45 - $23.81
Q3 2023	13,553	$280	$25.37	$20.52 - $30.79